Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.33 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.33 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5413351 | 1.00 | KMT2A (0.48) | KMT2AMEN1MAPTTHRBRECQL | |
| Sulfuric Acid SCHEMBL5406406 | 1.00 | KMT2A (0.48) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL27512702 | 0.95 | MEN1 (0.50) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL5712057 | 0.95 | MEN1 (0.50) | KMT2AMEN1MAPTTHRBRECQL | |
| Sulfuric Acid SCHEMBL5406403 | 0.94 | KMT2A (0.46) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL3144433 | 0.89 | KMT2A (0.47) | KMT2AMEN1MAPTTHRBRECQL | |
| Hydrochloric Acid SCHEMBL5405589 | 0.88 | KMT2A (0.46) | KMT2AMEN1MAPTTHRBRECQL | |
| Iodide SCHEMBL3430930 | 0.88 | KMT2A (0.46) | KMT2AMEN1MAPTTHRBRECQL | |
| Bromide SCHEMBL5405629 | 0.88 | KMT2A (0.46) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL4887842 | 0.86 | SMN1; SMN2 (0.40) | KMT2AMEN1MAPTTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214248-B1 | Multi-component kit and method for temporarily dyeing and later decolorizing hair | WELLA AG (DE) | 2007-05-08 | — | — | US | claimed |
| EP-1054657-B1 | AGENT FOR COLORING FIBERS | WELLA AG (DE) | 2004-01-07 | — | — | EP | claimed |
| US-7214248-B1 | Multi-component kit and method for temporarily dyeing and later decolorizing hair | WELLA AG (DE) | 2007-05-08 | — | — | US | disclosed |