Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16589358 | 1.00 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13555769 | 1.00 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3431819 | 1.00 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL16901579 | 1.00 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7955532 | 0.91 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7948319 | 0.91 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7955883 | 0.91 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4 | |
| Benzoic Acid SCHEMBL21175034 | 0.84 | SLC6A3 (0.58) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6743581 | 0.80 | KCNH2 (0.48) | — | |
| SCHEMBL13015335 | 0.80 | KCNH2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051980-B1 | Dopamine transporter imaging agents | HARVARD COLLEGE (US) | 2010-12-15 | — | — | EP | disclosed |
| US-20070009432-A1 | Boat tropanes | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-01-11 | — | — | US | disclosed |
| US-7105678-B2 | Boat tropanes | ORGANIX, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| EP-1429811-A4 | THEURAPEUTIC TROPANE COMPOUNDS | HARVARD COLLEGE (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1429811-A4 | THEURAPEUTIC TROPANE COMPOUNDS | HARVARD COLLEGE (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1518562-A2 | Dopamine transporter imaging agents | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1518561-A2 | Dopamine transporter imaging agents | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1429811-A1 | THEURAPEUTIC TROPANE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-1429811-A1 | THEURAPEUTIC TROPANE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2004-06-23 | — | — | EP | disclosed |
| US-20030125352-A1 | Therapeutic tropane compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2003-07-03 | — | — | US | disclosed |
| US-6548041-B1 | Diagnosis, therapy of central nervous system disorders | ORGANIX, INC. | 2003-04-15 | — | — | US | disclosed |
| WO-2003015830-A1 | THEURAPEUTIC TROPANE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2003-02-27 | — | — | WO | disclosed |
| WO-2003015830-A1 | THEURAPEUTIC TROPANE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2003-02-27 | — | — | WO | disclosed |
| US-20020131931-A1 | Boat tropanes | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2002-09-19 | — | — | US | disclosed |
| EP-1238978-A2 | Intermediates for the synthesis of radiolabelled tropanes | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1051980-A2 | Dopamine transporter imaging agents | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020131931-A1 | Boat tropanes | SLC6A3, SLC18A2, SLC6A4 | SLC6A3 1/4885SLC6A2 4/4885SLC6A4 3/4885 |
| US-20030125352-A1 | Therapeutic tropane compounds | HTT, GAP43, MAPT | SLC6A3 23/4885SLC6A2 9/4885SLC6A4 83/4885 |
| US-20070009432-A1 | Boat tropanes | SLC6A3, SLC18A2, SLC6A4 | SLC6A3 1/4885SLC6A2 4/4885SLC6A4 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.