Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729494 | 0.79 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL27360393 | 0.75 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL2386511 | 0.74 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL28228185 | 0.71 | MEN1 (0.38) | MEN1KMT2A | |
| SCHEMBL15173289 | 0.71 | HTR6 (0.40) | MEN1KMT2A | |
| SCHEMBL8789140 | 0.69 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL9711356 | 0.67 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL28180702 | 0.62 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL4028237 | 0.62 | — | — | |
| SCHEMBL23143621 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233479-A1 | DISPIRO TETRAOXANE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MALARIA AND/OR CANCER | Liverpool School of Tropical Medicine (GB) | 2010-09-29 | — | — | EP | disclosed |
| EP-2091935-A2 | DISPIRO TETRAOXANE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MALARIA AND/OR CANCER | Liverpool School of Tropical Medicine (GB) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008038030-A2 | DISPIRO TETRAOXANE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MALARIA AND/OR CANCER | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2008-04-03 | — | — | WO | disclosed |