SCHEMBL3432772

SCHEMBL3432772

CCCCCO[C@@]1(C(=O)O)C[C@H](O)[C@@H](N)[C@H]([C@H](O)[C@H](O)CO)O1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ SIGLEC7 Q9Y286 7/20 0.39
▸ CD22 P20273 4/20 0.39
▸ NANP Q8TBE9 1/20 0.37
▸ NEU1 Q99519 2/20 0.34
▸ NEU2 Q9Y3R4 2/20 0.34
▸ SELL P14151 1/20 0.34
▸ SELP P16109 1/20 0.34
▸ MAG P20916 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28082288 1.00 L3MBTL1 (0.42) L3MBTL1SIGLEC7CD22NANPNEU1
SCHEMBL15942922 0.99 L3MBTL1 (0.41) L3MBTL1SIGLEC7CD22NANPNEU1
Water SCHEMBL28266640 0.99 L3MBTL1 (0.41) L3MBTL1SIGLEC7CD22NANPNEU1
Demannose SCHEMBL28201653 0.92 L3MBTL1 (0.37) L3MBTL1SIGLEC7CD22NANPNEU1
SCHEMBL18733280 0.88 L3MBTL1 (0.46) L3MBTL1SIGLEC7CD22NANPSELL
SCHEMBL19106891 0.87 L3MBTL1 (0.42) L3MBTL1SIGLEC7CD22NANPNEU1
SCHEMBL5552033 0.85 L3MBTL1 (0.40) L3MBTL1CD22NANPNEU1NEU2
SCHEMBL5548413 0.84 L3MBTL1 (0.41) L3MBTL1SIGLEC7CD22NANPNEU1
SCHEMBL27992452 0.84 L3MBTL1 (0.41) L3MBTL1SIGLEC7CD22NANPNEU1
SCHEMBL16190386 0.83 NANP (0.50) L3MBTL1SIGLEC7CD22NANPNEU2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110402251-A Subtilase cytotoxin b subunit mutant UNIV GRIFFITH 2019-11-01 — — CN claimed
CN-110169454-A A kind of children's formula milk for being conducive to protect eyes and help brain intelligence development 上海育博营养食品有限公司 2019-08-27 — — CN claimed
CN-109161570-A A kind of method and fermentation liquid for improving fermentation and producing N-acetyl-neuraminate 武汉中科光谷绿色生物技术有限公司 2019-01-08 — — CN claimed
CN-108982493-A A kind of neuraminidase drying chemical reagent paper and preparation method thereof 迪瑞医疗科技股份有限公司 2018-12-11 — — CN claimed
CN-116003486-A Lead compound, preparation method thereof and application thereof in preparation of anti-influenza virus drugs 北京天之泰生物科技有限公司 2023-04-25 — — CN disclosed
CN-115552026-A Enzymatic method for preparing CMP-Neu5Ac 马克斯·普朗克科学促进学会 2022-12-30 — — CN disclosed
CN-110483637-B Anti-avian influenza virus neuraminidase N2 monoclonal antibody, encoding gene and application thereof 扬州大学 2022-06-10 — — CN disclosed
CN-108441461-B Recombinant bacterium for high yield of N-acetylneuraminic acid by utilizing artificial dual-carbon source 江南大学 2020-11-06 — — CN disclosed
CN-110402251-A Subtilase cytotoxin b subunit mutant UNIV GRIFFITH 2019-11-01 — — CN disclosed
CN-110129354-A A kind of specific biological sensor of N-acetyl-neuraminate and its application 江南大学 2019-08-16 — — CN disclosed
CN-109771316-A A kind of method and its application improving N-acetyl-neuraminate aqueous stability 中国科学院合肥物质科学研究院 2019-05-21 — — CN disclosed
CN-109744446-A A kind of lactalbumin class solid beverage and preparation method thereof containing N-acetyl-neuraminate 杭州海王生物工程有限公司 2019-05-14 — — CN disclosed
CN-104628794-B Method for separating and purifying N-acetylneuraminic acid produced by microbiological fermentation 武汉中科光谷绿色生物技术有限公司 2017-05-10 — — CN disclosed
CN-104144613-B For the method providing sialylated oligosaccharides 菲仕兰品牌有限公司 2016-11-09 — — CN disclosed
CN-105861288-A Method and apparatus for preparing N-acetylneuraminic acid 中国科学院微生物研究所 2016-08-17 — — CN disclosed
EP-2173166-A1 INHIBITORS OF POLYSIALIC ACID DE-N-ACETYLASE AND METHODS FOR USING THE SAME Children's Hospital & Research Center at Oakland (US) 2010-04-14 — — EP disclosed
WO-2009006591-A1 INHIBITORS OF POLYSIALIC ACID DE-N-ACETYLASE AND METHODS FOR USING THE SAME CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) 2009-01-08 — — WO disclosed
EP-1976554-A2 DE-N-ACETYL SIALIC ACID ANTIGENS, ANTIBODIES THERETO, AND METHODS OF USE IN CANCER THERAPY Children's Hospital & Research Center at Oakland (US) 2008-10-08 — — EP disclosed
WO-2007075921-A2 DE-N-ACETYL SIALIC ACID ANTIGENS, ANTIBODIES THERETO, AND METHODS OF USE IN CANCER THERAPY CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) 2007-07-05 — — WO disclosed
CN-1145909-A Anti-ganglioside monoclonal antibodies and their use in specific active immunotherapy of malignant tumors CENTRO INMUNOLOGIA MOLECULAR (CU) 1997-03-26 — — CN disclosed
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