Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 2/20 | 0.71 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.67 |
| ▸ | MARS1 | P56192 | 1/20 | 0.65 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.65 |
| ▸ | SRC | P12931 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.65 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.65 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.65 |
| ▸ | LDHA | P00338 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | FBP1 | P09467 | 1/20 | 0.65 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.65 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226454 | 0.90 | HINT1 (0.78) | PRKACAPLA2G2AMARS1P2RY1P2RY2 | |
| SCHEMBL1000840 | 0.90 | HINT1 (0.78) | PRKACAPLA2G2AMARS1P2RY1P2RY2 | |
| SCHEMBL6704430 | 0.89 | PRKACA (0.75) | PRKACAPLA2G2AMARS1P2RY1P2RY2 | |
| SCHEMBL7925039 | 0.88 | HSP90B1 (0.70) | PRKACAMARS1P2RY1P2RY2ADORA1 | |
| SCHEMBL10586180 | 0.87 | P2RY1 (0.68) | PRKACAMARS1P2RY1P2RY2ADORA1 | |
| SCHEMBL30637132 | 0.87 | P2RY1 (0.68) | PRKACAMARS1P2RY1P2RY2ADORA1 | |
| SCHEMBL11519682 | 0.87 | P2RY1 (0.68) | PRKACAMARS1P2RY1P2RY2ADORA1 | |
| SCHEMBL219554 | 0.87 | P2RY1 (0.71) | PRKACAMARS1P2RY1P2RY2ADORA1 | |
| SCHEMBL31001632 | 0.87 | P2RY1 (0.71) | PRKACAMARS1P2RY1P2RY2ADORA1 | |
| SCHEMBL11584743 | 0.87 | P2RY1 (0.71) | PRKACAMARS1P2RY1P2RY2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3024926-A1 | GENERATING DEFINITIVE ENDODERM AND PANCREATIC PROGENITOR CELLS | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone (US) | 2016-06-01 | — | — | EP | disclosed |
| WO-2015013653-A1 | GENERATING DEFINITIVE ENDODERM AND PANCREATIC PROGENITOR CELLS | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2015-01-29 | — | — | WO | disclosed |
| WO-2012068539-A1 | USE AND COMPOSITION OF QUERCETIN-3'-O-SULFATE FOR THERAPEUTIC TREATMENT | LIMERICK BIOPHARMA, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2010065959-A1 | METHOD OF PREPARING ADENOSINE-RESISTANT ANTI-TUMOR T LYMPHOCYTES FOR ADOPTIVE IMMUNOTHERAPY | NORTHEASTERN UNIVERSITY (US) | 2010-06-10 | — | — | WO | disclosed |