Trifluoromethanesulfonamide

Trifluoromethanesulfonamide

SCHEMBL3432925

CCCC[N+]1(C)CCCC1.NS(=O)(=O)C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 2/20 0.41
CA2 P00918 3/20 0.38
CA1 P00915 2/20 0.38
CA7 P43166 1/20 0.38
CA13 Q8N1Q1 1/20 0.38
EPHX1 P07099 1/20 0.36
LMNA P02545 3/20 0.34
APOBEC3A P31941 2/20 0.34
APOBEC3G Q9HC16 2/20 0.34
KMT2A Q03164 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonamide SCHEMBL2119076 1.00 BBOX1 (0.41) BBOX1CA2CA1CA7CA13
Trifluoromethanesulfonamide SCHEMBL3434700 0.89 CA1 (0.41) BBOX1CA2CA1CA7CA13
Trifluoromethanesulfonamide SCHEMBL28887116 0.88 CA1 (0.39) BBOX1CA2CA1CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL25387141 0.86 BBOX1 (0.44) BBOX1EPHX1LMNAAPOBEC3AAPOBEC3G
Trifluoromethanesulfonic Acid SCHEMBL246591 0.86 BBOX1 (0.41) BBOX1EPHX1LMNAAPOBEC3AAPOBEC3G
Trifluoromethanesulfonic Acid SCHEMBL30697434 0.86 BBOX1 (0.41) BBOX1EPHX1LMNAAPOBEC3AAPOBEC3G
Trifluoromethanesulfonic Acid SCHEMBL717623 0.85 BBOX1 (0.40) BBOX1EPHX1LMNAAPOBEC3AAPOBEC3G
Trifluoromethanesulfonic Acid SCHEMBL318063 0.85 BBOX1 (0.40) BBOX1EPHX1LMNAAPOBEC3AAPOBEC3G
SCHEMBL301929 0.83 EPHX1 (0.41) BBOX1EPHX1LMNAAPOBEC3AAPOBEC3G
SCHEMBL179865 0.83 BBOX1 (0.39) BBOX1EPHX1LMNAAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841406-B2 Branched rod-coil polyimide—poly( alkylene oxide) copolymers and electrolyte compositions THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2014-09-23 US disclosed
US-20100159335-A1 Branched rod-coil polyimide - poly( alkylene oxide) copolymers and electrolyte compositions UNITED STATES GOVERNMENT AS REPRESENTED BY THE ADMINSRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION, WASHINGTON, D.C. (US) 2010-06-24 US disclosed