SCHEMBL3433017

SCHEMBL3433017

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)N1C(F)(F)C(F)(F)OC(F)(F)C1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9446874 1.00
SCHEMBL3435200 1.00
SCHEMBL20497355 0.98
SCHEMBL143546 0.91
SCHEMBL8606243 0.91
SCHEMBL8605913 0.86
SCHEMBL4911427 0.81
SCHEMBL11783987 0.81 LMNA (0.30)
SCHEMBL8606249 0.80
SCHEMBL10948995 0.79 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100055067-A1 PERFLUOROCARBON CONJUGATE AS A BLOOD SUBSTITUTE SNU R&DB FOUNDATION 2010-03-04 US claimed
EP-0415264-B1 Process for the preparation of perfluorinated heterocyclic compounds and compounds prepared by this process KALI CHEMIE AG (DE) 1994-06-29 EP claimed
EP-0415263-B1 Stabilisation of perfluorocarbon emulsions and perfluorinated heterocyclic compounds usable as emulsion stabilising additives KALI CHEMIE AG (DE) 1994-06-15 EP claimed
US-5173512-A An aqueous oil-in-water emulsion of perfluoro-N-cyclohexylmorpholine or a mixture with perfluoro-N-hexylmorpholine; synthetic blood KALI-CHEMIE AG (DE) 1992-12-22 US claimed
US-5120731-A For use as oxygen carriers in blood substitutes KALIE-CHEMIE AG (DE) 1992-06-09 US claimed
EP-0415264-A2 Process for the preparation of perfluorinated heterocyclic compounds and compounds prepared by this process Kali-Chemie Aktiengesellschaft (DE) 1991-03-06 EP claimed
EP-0033402-B1 PERFUSATE FOR PRESERVING ORGAN TO BE TRANSPLANTED AND PRESERVING METHOD The Green Cross Corporation (JP) 1983-09-07 EP claimed
US-4285928-A AN EMULSION OF AN X-RAY CONTRAST AGENT AND A MIXTURE OF PERFLUORO COMPOUNDS HAVING OXYGEN-CARRYING ABILITIES Wada, Juro (JP) 1981-08-25 US claimed
EP-0033402-A1 Perfusate for preserving organ to be transplanted and preserving method The Green Cross Corporation (JP) 1981-08-12 EP claimed
US-4186253-A RINGER'S SOLUTION WITH INCREASED POTASSIUM ION, ALBUMIN, PERFLUOROCARBON COMPOUND, EMULSIFIER THE GREEN CROSS CORPORATION (JP) 1980-01-29 US claimed
US-3962439-A PERFLUOROCARBON COMPOUNDS THE GREEN CROSS CORPORATION (JA) 1976-06-08 US claimed
US-20100055067-A1 PERFLUOROCARBON CONJUGATE AS A BLOOD SUBSTITUTE SNU R&DB FOUNDATION 2010-03-04 US disclosed
EP-0415264-B1 Process for the preparation of perfluorinated heterocyclic compounds and compounds prepared by this process KALI CHEMIE AG (DE) 1994-06-29 EP disclosed
EP-0415263-B1 Stabilisation of perfluorocarbon emulsions and perfluorinated heterocyclic compounds usable as emulsion stabilising additives KALI CHEMIE AG (DE) 1994-06-15 EP disclosed
US-5262442-A Fluosol for injection for oxygen transport ALPHA THERAPEUTIC CORPORATION (US) 1993-11-16 US disclosed
US-4285928-A AN EMULSION OF AN X-RAY CONTRAST AGENT AND A MIXTURE OF PERFLUORO COMPOUNDS HAVING OXYGEN-CARRYING ABILITIES Wada, Juro (JP) 1981-08-25 US disclosed
EP-0033402-A1 Perfusate for preserving organ to be transplanted and preserving method The Green Cross Corporation (JP) 1981-08-12 EP disclosed
US-4186253-A RINGER'S SOLUTION WITH INCREASED POTASSIUM ION, ALBUMIN, PERFLUOROCARBON COMPOUND, EMULSIFIER THE GREEN CROSS CORPORATION (JP) 1980-01-29 US disclosed
US-3993581-A WITH A PHOSPHOLIPID AS EMULSIFIER AND A FATTY ACID, ALKALI METAL SALT OR ITS MONOGLYCERIDE AS AN ADJUVANT THE GREEN CROSS CORPORATION (JA) 1976-11-23 US disclosed
US-3962439-A PERFLUOROCARBON COMPOUNDS THE GREEN CROSS CORPORATION (JA) 1976-06-08 US disclosed