SCHEMBL3433430

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3394773	0.92	EGFR (0.81)	EGFRERBB2
	SCHEMBL29623598	0.91	EGFR (0.69)	EGFRERBB2
	SCHEMBL185131	0.91	EGFR (0.69)	EGFRERBB2
	SCHEMBL14489912	0.91	EGFR (0.72)	EGFRERBB2
	SCHEMBL16606121	0.91	EGFR (1.00)	EGFRERBB2
	SCHEMBL1943518	0.89	EGFR (0.69)	EGFRERBB2
	SCHEMBL12754569	0.89	EGFR (0.67)	EGFRERBB2
	SCHEMBL3395788	0.89	EGFR (1.00)	EGFRERBB2
	SCHEMBL16075707	0.89	EGFR (1.00)	EGFRERBB2
	SCHEMBL14489872	0.89	EGFR (0.66)	EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.