Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CALML3 | P27482 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196364 | 1.00 | MAOA (0.46) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3196372 | 1.00 | MAOA (0.46) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3200391 | 0.94 | MAOA (0.46) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3200394 | 0.94 | MAOA (0.46) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3201167 | 0.93 | MAOA (0.49) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3201174 | 0.93 | MAOA (0.49) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3209291 | 0.89 | MAOA (0.49) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3209292 | 0.89 | MAOA (0.49) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3212196 | 0.89 | MAOA (0.49) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3212190 | 0.89 | MAOA (0.49) | MAOAMAOBCALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254892-A1 | BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES | Global Alliance For Tb Drug Development (US) | 2010-12-01 | — | — | EP | claimed |
| WO-2009120789-A1 | BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2009-10-01 | — | — | WO | claimed |