Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 18/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285016 | 0.91 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL1284946 | 0.90 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL1285151 | 0.88 | MTNR1A (0.55) | MTNR1AMTNR1B | |
| SCHEMBL1285974 | 0.88 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL1285348 | 0.88 | MTNR1A (0.72) | MTNR1AMTNR1BGAA | |
| SCHEMBL3432115 | 0.87 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL1696500 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL1284205 | 0.85 | MTNR1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL3426737 | 0.84 | MTNR1A (0.54) | MTNR1AMTNR1B | |
| SCHEMBL1286502 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266975-A1 | 1-(2-alkyl-2,3-dihydro-benzofuran-4-yl)-pyrrolidin-3-ylamine acyl compounds | Ferrer Internacional, S.A. (ES) | 2010-12-29 | — | — | EP | disclosed |
| WO-2010145989-A1 | 1-(2-ALKYL-2,3-DIHYDRO-BENZOFURAN-4-YL)-PYRROLIDIN-3-YLAMINE ACYL COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2010-12-23 | — | — | WO | disclosed |