Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866011 | 0.95 | DYRK1A (0.39) | DYRK1ACA2ITKAPPMAPT | |
| SCHEMBL2855117 | 0.92 | CA2 (0.40) | DYRK1ACA2MAPTMEN1KMT2A | |
| SCHEMBL2859515 | 0.83 | CA2 (0.37) | CA2APPMAPTGSK3BMEN1 | |
| SCHEMBL544321 | 0.83 | MAPT (0.38) | CA2MAPTMEN1KMT2APOLB | |
| SCHEMBL2869556 | 0.81 | MAPT (0.40) | CA2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL2859668 | 0.81 | GSK3B (0.37) | DYRK1ACA2ITKAPPGSK3B | |
| SCHEMBL2862832 | 0.80 | CA2 (0.47) | CA2 | |
| SCHEMBL2855233 | 0.80 | MAPT (0.45) | DYRK1ACA2MAPT | |
| SCHEMBL3404963 | 0.79 | MAPT (0.35) | CYP11B1CYP11B2CA2MAPTGSK3B | |
| SCHEMBL2854987 | 0.78 | MAPT (0.47) | DYRK1AAPPSIRT2MAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |