Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10263650 | 0.80 | USP7 (0.34) | USP7SCN5A | |
| SCHEMBL10203078 | 0.76 | SCN5A (0.34) | USP7SCN5A | |
| SCHEMBL24258830 | 0.72 | USP7 (0.33) | USP7SCN5A | |
| SCHEMBL24258819 | 0.70 | SCN5A (0.31) | SCN5A | |
| SCHEMBL21009025 | 0.68 | — | — | |
| SCHEMBL3424196 | 0.66 | KMO (0.35) | USP7 | |
| SCHEMBL3510382 | 0.66 | — | — | |
| SCHEMBL8429341 | 0.66 | — | — | |
| SCHEMBL3422558 | 0.65 | ABL1 (0.37) | USP7 | |
| SCHEMBL24258815 | 0.65 | HPGD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588197-B1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2012003392-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |