Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TAF1 | P21675 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432621 | 0.84 | BRD4 (0.50) | BRD4PTGER4AAK1ALDH1A1KDM4E | |
| SCHEMBL3474602 | 0.83 | BRD4 (0.49) | BRD4PTGER4AAK1ALDH1A1KDM4E | |
| SCHEMBL3474853 | 0.79 | PDE4A (0.43) | ALDH1A1KDM4EHPGDPDE4APDE4B | |
| SCHEMBL3377379 | 0.76 | BRD4 (0.48) | BRD4PTGER4AAK1ALDH1A1KDM4E | |
| SCHEMBL3476109 | 0.75 | BRD4 (0.47) | BRD4AAK1ALDH1A1KDM4EHPGD | |
| SCHEMBL3377915 | 0.74 | CYP1A2 (0.45) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3380246 | 0.74 | HDAC6 (0.56) | ALDH1A1KDM4EHPGDPOLBCYP2C9 | |
| SCHEMBL3380300 | 0.72 | KDM4E (0.46) | ALDH1A1KDM4EHPGDPDE4DPOLB | |
| SCHEMBL3435619 | 0.72 | TDP2 (0.40) | BRD4AAK1SMN1; SMN2CYP3A4 | |
| SCHEMBL3434978 | 0.72 | AAK1 (0.42) | BRD4AAK1TAF1BRD2BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |