Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436581 | 0.88 | ALDH1A1 (0.38) | HSP90AA1HSP90AB1SCN9ACYP1A2CYP3A4 | |
| SCHEMBL3436005 | 0.84 | MAPK1 (0.36) | HSP90AA1HSP90AB1SCN9ACYP3A4GAA | |
| SCHEMBL14000118 | 0.83 | ALDH1A1 (0.32) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3436197 | 0.76 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL13999802 | 0.74 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1SCN9ACYP1A2CYP3A4 | |
| SCHEMBL13999778 | 0.73 | GAA (0.39) | SCN9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3434442 | 0.73 | POLB (0.38) | SCN9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2077266 | 0.71 | GAA (0.40) | HSP90AA1HSP90AB1SCN9ACYP1A2CYP3A4 | |
| SCHEMBL3435589 | 0.71 | GAA (0.43) | HSP90AA1HSP90AB1SCN9ACYP1A2CYP3A4 | |
| SCHEMBL3556808 | 0.70 | AOC3 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | HSP90AA1 3446/4885HSP90AB1 3216/4885SCN9A 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.