Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.66 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxycinchophen SCHEMBL1170683 | 0.80 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| Oxycinchophen SCHEMBL29460357 | 0.80 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL9439421 | 0.80 | DHODH (0.76) | DHODHPDE10AMEN1KMT2ALMNA | |
| Oxycinchophen SCHEMBL31654029 | 0.80 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL13971502 | 0.77 | DHODH (0.77) | DHODHPDE10AMEN1KMT2ALMNA | |
| SCHEMBL4601632 | 0.77 | DHODH (0.77) | DHODHPDE10AMEN1KMT2ALMNA | |
| SCHEMBL9501979 | 0.77 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| Acridone SCHEMBL243819 | 0.77 | KDM4E (0.56) | DHODHPDE10AMEN1KMT2ALMNA | |
| SCHEMBL28731733 | 0.76 | NPC1 (0.56) | DHODHPDE10AADORA2AMAPTTSHR | |
| SCHEMBL9630011 | 0.76 | RAB9A (0.50) | DHODHPDE10AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247558-A1 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | Siemens Medical Solutions USA, Inc. (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009102498-A1 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| US-6156946-A | Biological activation of aromatics for chemical processing and/or upgrading of aromatic compounds, petroleum, coal, resid, bitumen and other petrochemical streams | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 2000-12-05 | — | — | US | disclosed |