Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298922 | 0.92 | CYP19A1 (0.34) | MERTKAGTR1AGTR2CYP19A1CYP2C9 | |
| SCHEMBL2297327 | 0.92 | BDKRB1 (0.31) | BDKRB1 | |
| SCHEMBL4023230 | 0.83 | BDKRB1 (0.30) | BDKRB1 | |
| SCHEMBL2300156 | 0.78 | TRPV1 (0.31) | — | |
| SCHEMBL2296168 | 0.77 | TLR8 (0.33) | — | |
| SCHEMBL2297871 | 0.74 | SCARB1 (0.32) | — | |
| SCHEMBL2295297 | 0.73 | TLR8 (0.30) | — | |
| SCHEMBL2298915 | 0.72 | FABP4 (0.33) | — | |
| SCHEMBL2296228 | 0.72 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL2297325 | 0.72 | BDKRB1 (0.31) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2244711-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Cytokinetics, Incorporated (US) | 2010-11-03 | — | — | EP | disclosed |