Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432670 | 0.95 | PDGFRB (0.70) | HRH3PDGFRBPDGFRABCHEMAOA | |
| SCHEMBL31159541 | 0.90 | HRH3 (0.66) | HRH3PDGFRBPDGFRABCHEMAOA | |
| SCHEMBL13460792 | 0.86 | HRH3 (0.73) | HRH3PDGFRBPDGFRAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3435039 | 0.85 | HRH3 (0.71) | HRH3PDGFRBPDGFRAALDH1A1KDM4E | |
| SCHEMBL31159513 | 0.85 | BCHE (0.56) | HRH3PDGFRBPDGFRABCHEMAOA | |
| SCHEMBL5843451 | 0.83 | ALDH1A1 (0.58) | HRH3ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL862913 | 0.83 | KDM4E (0.74) | HRH3PDGFRBPDGFRABCHEMAOA | |
| SCHEMBL12848573 | 0.82 | PDGFRB (0.73) | HRH3PDGFRBPDGFRAALDH1A1KDM4E | |
| SCHEMBL15623125 | 0.82 | PDGFRB (0.76) | HRH3PDGFRBPDGFRAALDH1A1KDM4E | |
| SCHEMBL13460610 | 0.82 | HRH3 (0.60) | HRH3PDGFRBPDGFRAMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027280-A1 | NITROBENZINDOLES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-03-11 | — | — | WO | disclosed |