Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.75 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.66 |
| ▸ | KDR | P35968 | 4/20 | 0.63 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.63 |
| ▸ | AURKA | O14965 | 1/20 | 0.63 |
| ▸ | INSR | P06213 | 1/20 | 0.63 |
| ▸ | FBP1 | P09467 | 1/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.63 |
| ▸ | FLT4 | P35916 | 1/20 | 0.63 |
| ▸ | CLK1 | P49759 | 1/20 | 0.63 |
| ▸ | TEK | Q02763 | 1/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.63 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.63 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.57 |
| ▸ | FLT1 | P17948 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390855 | 1.00 | EGFR (0.75) | EGFRERBB2KDREPHB4AURKA | |
| SCHEMBL3394991 | 0.95 | EGFR (0.78) | EGFRERBB2KDREPHB4AURKA | |
| SCHEMBL10285885 | 0.90 | EGFR (0.81) | EGFRERBB2KDREPHB4AURKA | |
| SCHEMBL12743397 | 0.87 | EGFR (0.92) | EGFRERBB2KDREPHB4AURKA | |
| SCHEMBL3395232 | 0.87 | EGFR (0.64) | EGFRERBB2KDREPHB4EPHA2 | |
| SCHEMBL3390840 | 0.86 | EGFR (0.72) | EGFRERBB2KDREPHB4EPHA2 | |
| SCHEMBL3394869 | 0.86 | EGFR (0.75) | EGFRERBB2EPHB4EPHA2 | |
| SCHEMBL29623536 | 0.86 | EGFR (1.00) | EGFRERBB2KDREPHB4AURKA | |
| SCHEMBL185721 | 0.86 | EGFR (1.00) | EGFRERBB2KDREPHB4AURKA | |
| SCHEMBL3391778 | 0.86 | EGFR (0.65) | EGFRERBB2KDREPHB4EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167492-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | Hanmi Pharm. Co., Ltd. (KR) | 2010-03-31 | — | — | EP | claimed |
| WO-2008150118-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | claimed |