Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 12/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432056 | 0.70 | DPP4 (0.45) | SCN9ADPP4 | |
| SCHEMBL3434677 | 0.69 | SCN9A (0.39) | SCN9ADPP4 | |
| SCHEMBL19500634 | 0.67 | DPP4 (0.43) | DPP4ATM | |
| SCHEMBL29364846 | 0.67 | DPP4 (0.43) | DPP4ATM | |
| SCHEMBL344599 | 0.67 | DPP4 (0.43) | DPP4ATM | |
| SCHEMBL344600 | 0.67 | DPP4 (0.43) | DPP4ATM | |
| SCHEMBL342707 | 0.67 | DPP4 (0.43) | DPP4ATM | |
| SCHEMBL28759095 | 0.67 | DPP4 (0.43) | DPP4ATM | |
| SCHEMBL342708 | 0.67 | DPP4 (0.43) | DPP4ATM | |
| SCHEMBL8269365 | 0.66 | DPP4 (0.43) | DPP4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250157-A1 | NOVEL HETEROCYCLIC COMPOUNDS | Panacea Biotec Limited (IN) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009093269-A1 | NOVEL HETEROCYCLIC COMPOUNDS | PANACEA BIOTEC LIMITED (IN) | 2009-07-30 | — | — | WO | disclosed |