Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326293 | 0.86 | KMT2A (0.46) | KMT2AACACBKIF11ABL1HRH3 | |
| SCHEMBL28202712 | 0.81 | KMT2A (0.45) | KMT2AACACBKIF11ABL1GAA | |
| SCHEMBL5196227 | 0.81 | KMT2A (0.48) | KMT2AACACBHDAC1KIF11ABL1 | |
| SCHEMBL9331210 | 0.80 | KMT2A (0.47) | KMT2AACACBABL1ICAM1SELE | |
| SCHEMBL2780654 | 0.79 | — | — | |
| SCHEMBL343489 | 0.79 | — | — | |
| SCHEMBL3425315 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL23411737 | 0.77 | KMT2A (0.51) | KMT2AACACBHDAC1HDAC6KIF11 | |
| SCHEMBL24568381 | 0.76 | ACACB (0.55) | KMT2AACACBKIF11GAAALDH1A1 | |
| SCHEMBL15296855 | 0.76 | KMT2A (0.44) | KMT2AACACBHDAC1KIF11ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | claimed |
| US-12583851-B2 | Heteroaryl-substituted pyrazine derivatives as pesticides | ELANCO ANIMAL HEALTH GMBH (DE) | 2026-03-24 | — | — | US | disclosed |
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |
| US-20230145481-A1 | SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS | DICE ALPHA, INC. | 2023-05-11 | — | — | US | disclosed |
| US-20230101819-A1 | SMYD Inhibitors | EPIZYME INC (US) | 2023-03-30 | — | — | US | disclosed |
| CN-109071526-B | Acid addition salts of piperazine derivatives | 阿森纽荣股份公司 | 2023-02-28 | — | — | CN | disclosed |
| US-20230023326-A1 | HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | disclosed |
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | disclosed |
| US-10266526-B2 | Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer | Epizyme, Inc. (US) | 2019-04-23 | — | — | US | disclosed |
| EP-3419976-A1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | Asceneuron SA (CH) | 2019-01-02 | — | — | EP | disclosed |
| CN-109071526-A | The acid-addition salts of bridged piperazine derivatives | 阿森纽荣股份公司 | 2018-12-21 | — | — | CN | disclosed |
| US-20170355695-A1 | SMYD Inhibitors | Epizyme, Inc. (US) | 2017-12-14 | — | — | US | disclosed |
| WO-2017144637-A1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |
| CN-107108601-A | Glycosidase inhibitor | 阿森纽荣股份公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-103998434-A | Thiazole derivative as DHODH inhibitor and use thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-08-20 | — | — | CN | disclosed |
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583851-B2 | Heteroaryl-substituted pyrazine derivatives as pesticides | CBR3, CYCS, CWC15 | KMT2A 3192/4885ACACB 1541/4885HDAC4 1882/4885 |
| US-20230023326-A1 | HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | DDT, PRXL2A, CAT | KMT2A 2752/4885ACACB 4127/4885HDAC4 2508/4885 |
| US-20230145481-A1 | SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS | IL17A, IL2, IL23R | KMT2A 3300/4885ACACB 594/4885HDAC4 896/4885 |
| US-10266526-B2 | Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer | SMYD3, SMYD2, SNRPD3 | KMT2A 360/4885ACACB 2316/4885HDAC4 705/4885 |
| US-20170355695-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | KMT2A 348/4885ACACB 1838/4885HDAC4 1369/4885 |
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | KMT2A 355/4885ACACB 1909/4885HDAC4 1391/4885 |
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | KMT2A 420/4885ACACB 2377/4885HDAC4 2422/4885 |
| US-20230101819-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | KMT2A 364/4885ACACB 1837/4885HDAC4 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.