Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12486284 | 1.00 | HSD17B10 (0.48) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| SCHEMBL1427524 | 1.00 | HSD17B10 (0.48) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| Methane SCHEMBL6697096 | 0.98 | HSD17B10 (0.47) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| SCHEMBL29126181 | 0.98 | HPGD (0.50) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| SCHEMBL31459726 | 0.98 | HPGD (0.50) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| SCHEMBL1115598 | 0.95 | HSD17B10 (0.52) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| SCHEMBL559852 | 0.95 | HSD17B10 (0.52) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| SCHEMBL1010839 | 0.95 | HSD17B10 (0.52) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| SCHEMBL1550543 | 0.95 | HSD17B10 (0.52) | HSD17B10HPGDEPHX1CHRM2CHRM1 | |
| Methane SCHEMBL667082 | 0.93 | HSD17B10 (0.51) | HSD17B10HPGDEPHX1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114410619-B | Method for synthesizing (S) -N-Boc-hydroxy piperidine by immobilized biocatalyst | 东南大学成贤学院 | 2023-12-15 | — | — | CN | claimed |
| CN-114410619-A | Method for synthesizing (S) -N-Boc-hydroxypiperidine by immobilized biocatalyst | 东南大学成贤学院 | 2022-04-29 | — | — | CN | claimed |
| CN-114410619-B | Method for synthesizing (S) -N-Boc-hydroxy piperidine by immobilized biocatalyst | 东南大学成贤学院 | 2023-12-15 | — | — | CN | disclosed |
| CN-114410619-B | Method for synthesizing (S) -N-Boc-hydroxy piperidine by immobilized biocatalyst | 东南大学成贤学院 | 2023-12-15 | — | — | CN | disclosed |
| CN-114410619-B | Method for synthesizing (S) -N-Boc-hydroxy piperidine by immobilized biocatalyst | 东南大学成贤学院 | 2023-12-15 | — | — | CN | disclosed |
| CN-114410619-A | Method for synthesizing (S) -N-Boc-hydroxypiperidine by immobilized biocatalyst | 东南大学成贤学院 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410619-A | Method for synthesizing (S) -N-Boc-hydroxypiperidine by immobilized biocatalyst | 东南大学成贤学院 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410619-A | Method for synthesizing (S) -N-Boc-hydroxypiperidine by immobilized biocatalyst | 东南大学成贤学院 | 2022-04-29 | — | — | CN | disclosed |
| CN-105821013-B | Carbonyl reductase and its application in the chiral N-protected-hydroxyl azacyclo- of preparation | 华东理工大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-109232581-A | The method for replacing Buddhist nun's intermediate according to Shandong is isolated and purified with zinc chloride | 福建省微生物研究所 | 2019-01-18 | — | — | CN | disclosed |
| CN-106967071-A | It is a kind of according to Shandong replace Buddhist nun's intermediate isolation and purification method | 福建省微生物研究所 | 2017-07-21 | — | — | CN | disclosed |
| CN-105821013-A | Carbonyl reductase and application thereof in preparation of Chiral N-protecting-hydroxy nitrogen heterocycle | 华东理工大学 | 2016-08-03 | — | — | CN | disclosed |
| EP-2220086-A2 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS ACTIVE AGENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082134-A2 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS ACTIVE AGENT | LG LIFE SCIENCES, LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |