SCHEMBL559852

SCHEMBL559852

CC(C)(C)OC(=O)N1CCCC1O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.52
CHRM2 P08172 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.45
ALDH1A1 P00352 2/20 0.45
LMNA P02545 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
EPHX1 P07099 1/20 0.43
UCHL1 P09936 1/20 0.42
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1010839 1.00 HSD17B10 (0.52) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL1550543 1.00 HSD17B10 (0.52) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL1115598 1.00 HSD17B10 (0.52) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
Methane SCHEMBL667082 0.98 HSD17B10 (0.51) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL3434909 0.95 HSD17B10 (0.48) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL12486284 0.95 HSD17B10 (0.48) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL1427524 0.95 HSD17B10 (0.48) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL31459726 0.93 HPGD (0.50) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
Methane SCHEMBL6697096 0.93 HSD17B10 (0.47) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2
SCHEMBL29126181 0.93 HPGD (0.50) HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120054230-A Preparation method and application of covalent organic framework bipolar membrane 浙江大学 2025-05-30 CN claimed
CN-115611857-A Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine 上海伍夫科技有限公司 2023-01-17 CN claimed
US-20120035238-A1 COMPOUNDS AND METHODS FOR TREATING CANCER AND VIRAL INFECTIONS GOFF HILL LIMITED (BB) 2012-02-09 US claimed
EP-2403496-A1 COMPOUNDS AND METHODS FOR TREATING CANCER AND VIRAL INFECTIONS Goff Hill Limited (BB) 2012-01-11 EP claimed
WO-2010099600-A1 COMPOUNDS AND METHODS FOR TREATING CANCER AND VIRAL INFECTIONS TUCKER WILLIAM G (CA) 2010-09-10 WO claimed
US-20260138977-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12612396-B1 Modulators of beta catenin and uses thereof DEWPOINT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
CN-120054230-A Preparation method and application of covalent organic framework bipolar membrane 浙江大学 2025-05-30 CN disclosed
WO-2025094035-A1 TOLL-LIKE RECEPTOR AGONISTS AND CONJUGATES THEREOF PFIZER INC. (US) 2025-05-08 WO disclosed
US-20240109896-A1 FGFR KINASE INHIBITOR AND USE THEREOF YA THERAPEUTICS INC (CN) 2024-04-04 US disclosed
WO-2024001839-A1 HETEROAROMATIC RING COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-01-04 WO disclosed
US-20230174514-A1 AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2023-06-08 US disclosed
US-6531598-B1 Naphthostyrils HOFFMANN-LA ROCHE INC. 2003-03-11 US disclosed
US-6504034-B2 Cell antiproliferative agents; anticancer agents HOFFMANN-LA ROCHE INC. 2003-01-07 US disclosed
WO-2002085925-A2 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2002-10-31 WO disclosed
US-20020147343-A1 Naphthostyrils CHEN YI (US) 2002-10-10 US disclosed
WO-2002059109-A2 NAPHTHOSTYRIL DERIVATIVES AND THEIR USE AS INHIBITORS OF CYCLIN- DEPENDENT KINASES F. HOFFMANN-LA ROCHE AG (CH) 2002-08-01 WO disclosed
US-4634715-A CONVERTING ENZYME INHIBITORS MERCK & CO., INC. (US) 1987-01-06 US disclosed
EP-0058918-B1 AZA ANALOGS OF AMINOACID DERIVATIVES AS ANTIHYPERTENSIVES MERCK & CO. INC. (US) 1986-01-29 EP disclosed
EP-0058918-A1 Aza analogs of aminoacid derivatives as antihypertensives MERCK & CO. INC. (US) 1982-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109896-A1 FGFR KINASE INHIBITOR AND USE THEREOF FGFR1, FGFR2, FGFR3 HSD17B10 1223/4885CHRM2 4856/4885CHRM1 4874/4885
US-12612396-B1 Modulators of beta catenin and uses thereof CTNNB1, CTNND1, CTNNA1 HSD17B10 1763/4885CHRM2 4789/4885CHRM1 4854/4885
US-20020147343-A1 Naphthostyrils CCNI, CDKL1, CDK2 HSD17B10 1394/4885CHRM2 4598/4885CHRM1 4510/4885
US-20260138977-A1 MODULATORS OF BETA CATENIN AND USES THEREOF CTNNB1, CTNND1, CTNNA1 HSD17B10 1763/4885CHRM2 4789/4885CHRM1 4854/4885
US-20120035238-A1 COMPOUNDS AND METHODS FOR TREATING CANCER AND VIRAL INFECTIONS TP53, RNASE1, FURIN HSD17B10 807/4885CHRM2 4846/4885CHRM1 4815/4885
US-20230174514-A1 AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS CCR6, CCR1, CCR3 HSD17B10 3092/4885CHRM2 778/4885CHRM1 1048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.