Styrene

Styrene

SCHEMBL3435010

C=CCOC(=O)C(=C)C=C(C)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 3/20 0.42
MAPK1 P28482 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
CYP3A4 P08684 1/20 0.41
AKR1C3 P42330 1/20 0.41
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 7/20 0.37
TSHR P16473 3/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP2C9 P11712 1/20 0.37
PKM P14618 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.35
PTP4A3 O75365 1/20 0.34
PTP4A1 Q93096 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7121429 0.88 MEN1 (0.50) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL663891 0.86 TSHR (0.35) MAPTCYP3A4NPSR1TSHRPTP4A3
Styrene SCHEMBL251772 0.84 KDM4E (0.45) MEN1KMT2AMAPK1KDM4ELMNA
Styrene SCHEMBL88055 0.83 MEN1 (0.50) MEN1KMT2AMAPTMAPK1KDM4E
Styrene SCHEMBL8106691 0.82 MEN1 (0.40) MEN1KMT2AMAPTMAPK1KDM4E
Styrene SCHEMBL8676239 0.82 MEN1 (0.44) MEN1KMT2AMAPTMAPK1KDM4E
Styrene SCHEMBL8097084 0.82 TSHR (0.46) MAPTMAPK1KDM4ELMNACYP3A4
Styrene SCHEMBL4627611 0.81 KDM4E (0.43) MEN1KMT2AMAPK1KDM4ELMNA
Styrene SCHEMBL4287862 0.81 MEN1 (0.48) MEN1KMT2AMAPTMAPK1KDM4E
Styrene SCHEMBL17159768 0.80 AKR1C3 (0.41) MAPTKDM4ELMNACYP3A4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2252664-B1 ENCAPSULATED NANOSCALE PARTICLES OF ORGANIC PIGMENTS XEROX CORP (US) 2018-12-05 EP disclosed
EP-2260081-B1 SILICA ENCAPSULATED ORGANIC NANOPIGMENTS AND METHOD OF MAKING SAME XEROX CORP (US) 2014-11-26 EP disclosed
US-8815394-B2 Encapsulated nanoscale particles of organic pigments XEROX CORPORATION (US) 2014-08-26 US disclosed
US-8287637-B2 Silica encapsulated organic nanopigments and method of making same XEROX CORPORATION (US) 2012-10-16 US disclosed
EP-2260081-A1 SILICA ENCAPSULATED ORGANIC NANOPIGMENTS AND METHOD OF MAKING SAME Xerox Corporation (US) 2010-12-15 EP disclosed
EP-2252664-A1 ENCAPSULATED NANOSCALE PARTICLES OF ORGANIC PIGMENTS Xerox Corporation (US) 2010-11-24 EP disclosed
WO-2009148687-A1 SILICA ENCAPSULATED ORGANIC NANOPIGMENTS AND METHOD OF MAKING SAME XEROX CORPORATION (US) 2009-12-10 WO disclosed
WO-2009126388-A1 ENCAPSULATED NANOSCALE PARTICLES OF ORGANIC PIGMENTS XEROX CORPORATION (US) 2009-10-15 WO disclosed
US-20090246674-A1 SILICA ENCAPSULATED ORGANIC NANOPIGMENTS AND METHOD OF MAKING SAME XEROX CORPORATION (US) 2009-10-01 US disclosed
US-20090227711-A1 ENCAPSULATED NANOSCALE PARTICLES OF ORGANIC PIGMENTS XEROX CORPORATION (US) 2009-09-10 US disclosed