SCHEMBL663891

SCHEMBL663891

C=CCOC(=O)C(=C)C=C(C)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
PTP4A3 O75365 2/20 0.30
PTP4A1 Q93096 2/20 0.30
NPSR1 Q6W5P4 1/20 0.30
PTP4A2 Q12974 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL3435010 0.86 MEN1 (0.42) TSHRCYP3A4MAPTPTP4A3PTP4A1
SCHEMBL3807349 0.84 TSHR (0.34) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL432150 0.81 NPSR1 (0.42) TSHRMAPTNPSR1
Ammonia Solution, Strong SCHEMBL15128898 0.80 NPSR1 (0.41) TSHRMAPTNPSR1
SCHEMBL1075820 0.79 MAPT (0.42) TSHRCYP3A4TDP1MAPTCACNA1B
Acrylic Acid SCHEMBL3651329 0.79 NPSR1 (0.38) TSHRMAPTNPSR1
SCHEMBL1172956 0.79 MAPT (0.34) TSHRMAPTCACNA1BAPBA1
SCHEMBL610540 0.79 TSHR (0.38) TSHR
Methacrylic Acid SCHEMBL9069461 0.79 NPSR1 (0.40) TSHRMAPTNPSR1
SCHEMBL11805889 0.79 TSHR (0.40) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655059-A1 WATER SOLUBLE PACKAGE FILMS FOR ACIDIC PRODUCT AND METHOD FOR ADDING ACIDIC PRODUCT TO WATER SYSTEM General Electric Company (US) 2013-10-30 EP claimed
US-20130256237-A1 WATER SOLUBLE PACKAGE FILMS FOR ACIDIC HIGH WATER CONTENT PRODUCT AND METHOD OF PRODUCING THE SAME GENERAL ELECTRIC COMPANY 2013-10-03 US claimed
WO-2012083478-A1 WATER SOLUBLE PACKAGE FILMS FOR ACIDIC PRODUCT AND METHOD FOR ADDING ACIDIC PRODUCT TO WATER SYSTEM GENERAL ELECTRIC COMPANY (US) 2012-06-28 WO claimed
EP-1583803-B1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS BASF SE (DE) 2010-07-28 EP claimed
US-6867301-B2 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-15 US claimed
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORP. 2004-07-15 US claimed
CN-112702988-B Multi-layer cleaning composition 花王株式会社 2024-01-09 CN disclosed
CN-115400036-A Cleaning material composition 株式会社资生堂 2022-11-29 CN disclosed
US-11471707-B2 Multi-capsule compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2022-10-18 US disclosed
EP-4043540-A1 MULTI-CAPSULE COMPOSITIONS International Flavors & Fragrances Inc. (US) 2022-08-17 EP disclosed
EP-3608392-B1 MULTI-CAPSULE COMPOSITIONS INT FLAVORS & FRAGRANCES INC (US) 2022-01-05 EP disclosed
CN-112702988-A Multi-layer cleaning composition 花王株式会社 2021-04-23 CN disclosed
US-10682533-B2 Multi-capsule compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2020-06-16 US disclosed
US-20010035110-A1 Ink composition capable of realizing images possessing excellent color development and fixation SEIKO EPSON CORPORATION 2001-11-01 US disclosed
EP-1114851-A1 Ink composition capable of realizing images possessing excellent color development and fixation SEIKO EPSON CORPORATION (JP) 2001-07-11 EP disclosed
US-5686534-A Initiation system for the anionic polymerisation of (meth)acrylic monomers ELF ATOCHEM S.A. (FR) 1997-11-11 US disclosed
US-5677387-A Initiation system for the anionic polymerization of (meth)acrylic monomers ELF ATOCHEM S.A. (FR) 1997-10-14 US disclosed
EP-0202606-B1 IMMOBILIZED ENZYME HAVING REVERSIBLE SOLUBILITY TANABE SEIYAKU CO., LTD. (JP) 1991-03-27 EP disclosed
US-4783409-A Immobilized enzyme having reversible solubility TANABE SEIYAKU CO., LTD. (JP) 1988-11-08 US disclosed
EP-0202606-A2 Immobilized enzyme having reversible solubility TANABE SEIYAKU CO., LTD. (JP) 1986-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10682533-B2 Multi-capsule compositions CAPG, GNE, RIMKLA TSHR 4200/4885CYP3A4 3183/4885TDP1 4392/4885
US-11471707-B2 Multi-capsule compositions CAPG, GNE, RIMKLA TSHR 4200/4885CYP3A4 3183/4885TDP1 4392/4885
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments NDUFA6, NDUFS6, NDUFA3 TSHR 4164/4885CYP3A4 149/4885TDP1 1373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.