Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.69 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434038 | 0.98 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL388562 | 0.90 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL1537285 | 0.89 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL163444 | 0.89 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL153062 | 0.87 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28331180 | 0.87 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL3846866 | 0.86 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL9898388 | 0.86 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL1581156 | 0.86 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL6887974 | 0.86 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11043396-B2 | Chemical mechanical polish slurry and method of manufacture | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2021-06-22 | — | — | US | disclosed |
| US-20200289699-A1 | L-HISTIDINE AND VITAMIN B IN OPHTHALMIC SOLUTIONS | FXS VENTURES, LLC | 2020-09-17 | — | — | US | disclosed |
| US-RE45587-E1 | Vaccines comprising aluminum adjuvants and histidine | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2015-06-30 | — | — | US | disclosed |
| CN-103429948-A | Chemiluminescent device with time delay activation | CYALUME TECHNOLOGIES INC | 2013-12-04 | — | — | CN | disclosed |
| US-7754218-B2 | pH buffering stability; adjuvant adsorption; reduced antigen hydrolysis | Novartis Caccines and Diagnostics SRL (IT) | 2010-07-13 | — | — | US | disclosed |
| CN-101443272-A | Methods and compositions for controlled and sustained generation and delivery of peroxides | UNIV VIRGINIA COMMONWEALTH (US) | 2009-05-27 | — | — | CN | disclosed |
| US-20080160045-A1 | Vaccines Comprising Aluminum Adjuvants and Histidine | NOVARTIS VACCINES AND DIAGNOSTICS, S.R.L. (IT) | 2008-07-03 | — | — | US | disclosed |
| US-7348006-B2 | Vaccines comprising aluminium adjuvants and histidine | NOVARTIS VACCINES AND DIAGNOSTICS, S.R.L. (IT) | 2008-03-25 | — | — | US | disclosed |
| CN-100350972-C | Vaccine containing aluminum adjuvant and histidine | CHIRON SPA (IT) | 2007-11-28 | — | — | CN | disclosed |
| US-20050158334-A1 | Vaccines comprising aluminium adjuvants and histidine | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2005-07-21 | — | — | US | disclosed |
| CN-1535158-A | Vaccines comprising aluminium adjuvants and histidine | �����ɷ� | 2004-10-06 | — | — | CN | disclosed |