SCHEMBL343554

SCHEMBL343554

COC1=NCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11237860 0.97 NOS3 (0.42)
SCHEMBL5865181 0.97 NOS3 (0.42)
SCHEMBL2382858 0.97 NOS3 (0.42)
SCHEMBL5865174 0.97 NOS3 (0.42)
SCHEMBL5098521 0.97 NOS3 (0.42)
SCHEMBL2382862 0.97 NOS3 (0.42)
SCHEMBL8446266 0.97 NOS3 (0.42)
SCHEMBL5098524 0.97 NOS3 (0.42)
SCHEMBL8268847 0.97 NOS3 (0.42)
SCHEMBL9374974 0.97 NOS3 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0949247-B1 Process for the preparation of piperidinylidene derivatives TAKASAGO PERFUMERY CO LTD (JP) 2001-09-12 EP claimed
US-6008358-A Process for the preparation of piperidinylidene derivative TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-12-28 US claimed
EP-0949247-A1 Process for the preparation of piperidinylidene derivatives Takasago International Corporation (JP) 1999-10-13 EP claimed
JP-11286481-A None JP disclosed
EP-4658262-A1 BICYCLIC IMIDE COMPOUNDS AS TRPA1 INHIBITORS D.E. Shaw Research, LLC (US) 2025-12-10 EP disclosed
US-20250304552-A1 ASK1 INHIBITOR COMPOUNDS AND USES THEREOF SEAL ROCK THERAPEUTICS INC (US) 2025-10-02 US disclosed
US-20250235462-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM SCIENCES INC (KR) 2025-07-24 US disclosed
CN-119119079-A Pyrimidinone compounds, preparation method thereof, pharmaceutical composition and application thereof 上海深势唯思科技有限责任公司 2024-12-13 CN disclosed
US-12133529-B2 Herbicidal phenylethers BASF SE (DE) 2024-11-05 US disclosed
EP-4416150-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM Sciences Inc (KR) 2024-08-21 EP disclosed
WO-2024163333-A1 BICYCLIC IMIDE COMPOUNDS AS TRPA1 INHIBITORS D. E. SHAW RESEARCH, LLC (US) 2024-08-08 WO disclosed
US-4220771-A MORPHINE POTENTIATORS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1980-09-02 US disclosed
US-4153235-A HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC ACTIVITIES RICHARDSON-MERRELL INC. (US) 1979-05-08 US disclosed
US-4126613-A HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC RICHARDSON-MERRELL INC. (US) 1978-11-21 US disclosed
US-4126611-A HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC RICHARDSON-MERRELL INC. (US) 1978-11-21 US disclosed
US-4126612-A HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC Retter, Eugene O. (US) 1978-11-21 US disclosed
US-4126621-A HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC RICHARDSON-MERRELL INC. (US) 1978-11-21 US disclosed
US-4061746-A Lactamimide inhibitors of gastrointestinal hypersecretion RICHARDSON-MERRELL INC. (US) 1977-12-06 US disclosed
US-4025634-A N-(arylsulfonyl)-alpha-nitro-delta 2,alpha -piperidineacetamides SHELL OIL COMPANY (US) 1977-05-24 US disclosed
US-3963701-A DIURETIC, ANTICOAGULANT RICHARDSON-MERRELL INC. (US) 1976-06-15 US disclosed