Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20189964 | 0.82 | MAPT (0.50) | POLBMAPTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL3436153 | 0.81 | MAPT (0.68) | POLBMAPTL3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL3436045 | 0.80 | CYP3A4 (0.51) | POLBMAPTL3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL1940737 | 0.80 | CYP3A4 (0.67) | POLBMAPTL3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL14334947 | 0.79 | MAPT (0.48) | POLBMAPTALDH1A1TDP1CTPS1 | |
| SCHEMBL9425659 | 0.79 | MAPT (0.67) | POLBMAPTL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL1938489 | 0.79 | CYP3A4 (0.50) | POLBMAPTL3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL3436398 | 0.79 | CYP3A4 (0.50) | CYP3A4ALDH1A1TDP1LMNAGAA | |
| SCHEMBL20190115 | 0.78 | ALDH1A1 (0.58) | POLBMAPTALDH1A1TDP1CTPS1 | |
| SCHEMBL4438134 | 0.78 | MAPT (0.46) | POLBMAPTCYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | POLB 4512/4885MAPT 1330/4885L3MBTL1 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.