SCHEMBL34361

SCHEMBL34361

Nc1cccc(SSc2ccccc2N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
NPSR1 Q6W5P4 1/20 0.61
APOBEC3G Q9HC16 1/20 0.61
CYP3A4 P08684 3/20 0.41
CASP1 P29466 2/20 0.41
RECQL P46063 1/20 0.41
MAOA P21397 3/20 0.38
POLB P06746 1/20 0.37
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MGLL Q99685 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
PDE7A Q13946 2/20 0.35
ALDH1A1 P00352 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
CA12 O43570 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34540 0.83 CYP3A4 (0.58) MAPTMEN1KMT2ACYP3A4CASP1
SCHEMBL8151896 0.81 MAPT (0.76) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL34097 0.78 MEN1 (1.00) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL30063472 0.78 MEN1 (1.00) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL34564 0.78 MAPT (0.70) MAPTMEN1KMT2ANPSR1APOBEC3G
Hydrochloric Acid SCHEMBL3248165 0.76 MEN1 (0.94) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL34658 0.75 CYP3A4 (0.48) MAPTMEN1KMT2ACYP3A4CASP1
SCHEMBL9976795 0.74 CYP3A4 (0.52) MAPTMEN1KMT2ACYP3A4CASP1
SCHEMBL11802519 0.74 MAPT (0.48) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL11807454 0.74 HSD17B10 (0.48) MAPTMEN1KMT2ANPSR1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2290003-B1 Thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD (JP) 2016-09-28 EP disclosed
EP-2281852-B1 PNEUMATIC TIRE COMPRISING A FILM COMPOSED OF A THERMOPLASTIC ELASTOMER COMPOSITION AS INNER LINER YOKOHAMA RUBBER CO LTD (JP) 2016-03-09 EP disclosed
US-8536271-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-09-17 US disclosed
US-8378035-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-02-19 US disclosed
EP-2290003-A2 Thermoplastic elastomer composition The Yokohama Rubber Company, Limited (JP) 2011-03-02 EP disclosed
EP-2281852-A1 Thermoplastic elastomer composition The Yokohama Rubber Company, Limited (JP) 2011-02-09 EP disclosed
US-20110028651-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-02-03 US disclosed
US-20110028648-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-02-03 US disclosed