SCHEMBL34564

SCHEMBL34564

Nc1ccc(SSc2ccccc2N)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.70
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
NPSR1 Q6W5P4 2/20 0.70
APOBEC3G Q9HC16 1/20 0.70
CYP3A4 P08684 4/20 0.42
TSHR P16473 3/20 0.42
MAPK1 P28482 2/20 0.42
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.40
HPGD P15428 4/20 0.40
HSD17B10 Q99714 3/20 0.40
MGLL Q99685 1/20 0.40
FBP1 P09467 1/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
ALOX15 P16050 3/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8151896 0.86 MAPT (0.76) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL30063472 0.83 MEN1 (1.00) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL34097 0.83 MEN1 (1.00) MAPTMEN1KMT2ANPSR1APOBEC3G
Hydrochloric Acid SCHEMBL3248165 0.81 MEN1 (0.94) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL3095695 0.80 CYP3A4 (0.56) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL3246649 0.79 MAPT (0.67) MAPTMEN1KMT2ACYP3A4TSHR
SCHEMBL34346 0.78 CYP3A4 (0.65) MAPTMEN1KMT2ACYP3A4TSHR
SCHEMBL34361 0.78 MAPT (0.61) MAPTMEN1KMT2ANPSR1APOBEC3G
Hydrochloric Acid SCHEMBL3248171 0.75 CYP3A4 (0.61) MAPTMEN1KMT2ACYP3A4TSHR
SCHEMBL11802519 0.75 MAPT (0.48) MAPTMEN1KMT2ANPSR1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2290003-B1 Thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD (JP) 2016-09-28 EP disclosed
EP-2281852-B1 PNEUMATIC TIRE COMPRISING A FILM COMPOSED OF A THERMOPLASTIC ELASTOMER COMPOSITION AS INNER LINER YOKOHAMA RUBBER CO LTD (JP) 2016-03-09 EP disclosed
US-8536271-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-09-17 US disclosed
US-8378035-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-02-19 US disclosed
EP-2290003-A2 Thermoplastic elastomer composition The Yokohama Rubber Company, Limited (JP) 2011-03-02 EP disclosed
EP-2281852-A1 Thermoplastic elastomer composition The Yokohama Rubber Company, Limited (JP) 2011-02-09 EP disclosed
US-20110028651-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-02-03 US disclosed
US-20110028648-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-02-03 US disclosed
US-3940371-A HYDROLYTIC AND CHEMICAL STABILITY CASE LESLIE C 1976-02-24 US disclosed