Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.61 |
| ▸ | HPGDS | O60760 | 3/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170935 | 0.90 | HPGDS (0.61) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3547707 | 0.90 | HPGDS (0.61) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3436397 | 0.89 | HPGD (0.68) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12789158 | 0.89 | HPGD (0.69) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL25551135 | 0.89 | HPGD (0.53) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27966332 | 0.86 | HPGD (0.66) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL26453259 | 0.84 | HPGD (0.63) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12790089 | 0.83 | HPGD (0.69) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3436418 | 0.83 | HDAC2 (0.51) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL25510789 | 0.83 | HPGDS (0.49) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | HPGD 1166/4885CYP1A2 1955/4885CYP3A4 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.