Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LCAT | P04180 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 3/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436533 | 0.95 | TRPV1 (0.46) | TRPV1HSD11B1MALT1LCATKMT2A | |
| SCHEMBL3435676 | 0.87 | GRIN2D (0.39) | HSD11B1MALT1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL3436016 | 0.81 | GRIN2D (0.42) | HSD11B1MALT1L3MBTL1MEN1CYP3A4 | |
| SCHEMBL27684335 | 0.81 | MALT1 (0.41) | TRPV1MALT1L3MBTL1MEN1CYP3A4 | |
| SCHEMBL3436585 | 0.79 | TRPV1 (0.45) | TRPV1HSD11B1MALT1LCATKMT2A | |
| SCHEMBL10278274 | 0.79 | TRPV1 (0.45) | TRPV1HSD11B1MALT1L3MBTL1CYP1A2 | |
| SCHEMBL13999799 | 0.75 | HSD11B1 (0.41) | TRPV1HSD11B1MALT1LCATCYP1A2 | |
| SCHEMBL3436768 | 0.75 | TRPV1 (0.48) | TRPV1HSD11B1MALT1CYP3A4CYP2C19 | |
| SCHEMBL3436522 | 0.75 | TRPV1 (0.47) | TRPV1HSD11B1MALT1LCATKMT2A | |
| SCHEMBL15966094 | 0.74 | HSD11B1 (0.55) | TRPV1HSD11B1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | TRPV1 3/4885HSD11B1 3972/4885MALT1 1638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.