Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436488 | 0.83 | CYP1A2 (0.42) | ALDH1A1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL3436761 | 0.81 | CYP1A2 (0.38) | ALDH1A1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL3436523 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL3436610 | 0.78 | CYP1A2 (0.38) | ALDH1A1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL3436838 | 0.78 | MAPT (0.43) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL3436706 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL3436297 | 0.76 | KMT2A (0.47) | ALDH1A1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL3436494 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ATSHRHTT | |
| SCHEMBL3436485 | 0.73 | CYP1A2 (0.42) | ALDH1A1CYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL3436493 | 0.72 | KMT2A (0.47) | ALDH1A1GAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | ALDH1A1 975/4885CYP1A2 1955/4885CYP3A4 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.