SCHEMBL3437002

SCHEMBL3437002

CCOP(=O)(OP(=O)(O)O)OP(=O)(O)O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
PPARD Q03181 2/20 0.50
TDP1 Q9NUW8 2/20 0.45
FDPS P14324 1/20 0.45
BLM P54132 1/20 0.45
TP53 P04637 1/20 0.42
BTN3A1 O00481 3/20 0.39
LPAR3 Q9UBY5 4/20 0.38
LPAR1 Q92633 2/20 0.38
LPAR2 Q9HBW0 2/20 0.38
MVD P53602 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29056130 0.95 TSHR (0.55) TSHRPPARDTDP1FDPSBLM
SCHEMBL627985 0.95 TSHR (0.60) TSHRPPARDTDP1FDPSBLM
Ammonia Solution, Strong SCHEMBL29191386 0.93 TSHR (0.52) TSHRPPARDTDP1FDPSBLM
Ammonia Solution, Strong SCHEMBL628388 0.92 TSHR (0.57) TSHRPPARDTDP1FDPSBLM
Ammonia Solution, Strong SCHEMBL628385 0.92 TSHR (0.57) TSHRPPARDTDP1FDPSBLM
Ethylene Glycol SCHEMBL29066338 0.88 PPARD (0.56) TSHRPPARDTDP1FDPSBLM
SCHEMBL27830727 0.88 TSHR (0.52) TSHRPPARDTDP1FDPSBLM
SCHEMBL27372192 0.88 TSHR (0.52) TSHRPPARDTDP1FDPSBLM
SCHEMBL28287397 0.86 TSHR (0.50) TSHRPPARDTDP1FDPSBLM
Phosphoric Acid SCHEMBL27882561 0.86 TSHR (0.50) TSHRPPARDTDP1FDPSBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104225676-B Containing the application in osteochondral defect is repaired of the lithium nature material bioactive bracket 浙江大学 2016-08-24 CN claimed
CN-104415668-A Making method of organic-inorganic hybrid separating membrane DALIAN CHEMICAL PHYSICS INST 2015-03-18 CN claimed
CN-104225676-A Application of lithium-containing natural material bioactive scaffold in osteochondral defect repair UNIV ZHEJIANG 2014-12-24 CN claimed
CN-101843919-A Method for preparing hydroxyapatite/composite hole bioactive glass UNIV HARBIN NORMAL 2010-09-29 CN claimed
WO-2023185158-A1 PROCESSING APPARATUS FOR VACUUM HEAT-INSULATING PLATE, AEROGEL-MODIFIED POLYURETHANE FOAM THERMAL INSULATION PLATE, AND PREPARATION METHOD THEREFOR 重庆再升科技股份有限公司 2023-10-05 WO disclosed
CN-109355664-A A kind of copper surface phosphoric acid esters assembles concentration and its application 上海电力学院 2019-02-19 CN disclosed
CN-106633011-A Reaction type flame-retardant polyester polyol and preparation method thereof 山东诺威聚氨酯股份有限公司 2017-05-10 CN disclosed
CN-104225676-B Containing the application in osteochondral defect is repaired of the lithium nature material bioactive bracket 浙江大学 2016-08-24 CN disclosed
CN-104415668-A Making method of organic-inorganic hybrid separating membrane DALIAN CHEMICAL PHYSICS INST 2015-03-18 CN disclosed
CN-104225676-A Application of lithium-containing natural material bioactive scaffold in osteochondral defect repair UNIV ZHEJIANG 2014-12-24 CN disclosed
US-20100324280-A1 SODIUM ABSORPTION INHIBITOR, POTASSIUM ABSORPTION INHIBITOR, PHOSPHORUS ABSORPTION INHIBITOR AND PREVENTIVE AGENT, THERAPEUTIC AGENT AND FOOD CONTAINING THE SAME OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2010-12-23 US disclosed
US-7807653-B2 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2010-10-05 US disclosed
CN-101843919-A Method for preparing hydroxyapatite/composite hole bioactive glass UNIV HARBIN NORMAL 2010-09-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324280-A1 SODIUM ABSORPTION INHIBITOR, POTASSIUM ABSORPTION INHIBITOR, PHOSPHORUS ABSORPTION INHIBITOR AND PREVENTIVE AGENT, THERAPEUTIC AGENT AND FOOD CONTAINING THE SAME SLC20A1, ALPI, SLC34A1 TSHR 1678/4885PPARD 4387/4885TDP1 3691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.