Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438632 | 0.87 | ATM (0.36) | ATMPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL6447041 | 0.73 | ATM (0.47) | ATMPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL6447044 | 0.73 | ATM (0.47) | ATMPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL15957787 | 0.72 | ATM (0.42) | ATMPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL19400636 | 0.66 | — | — | |
| SCHEMBL23549956 | 0.65 | TP53 (0.36) | ATMPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL28266385 | 0.64 | TP53 (0.35) | ATMPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL27564583 | 0.63 | — | — | |
| SCHEMBL29187988 | 0.63 | TP53 (0.35) | ATMPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL24851098 | 0.63 | TP53 (0.35) | ATMPOLBOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809557-B2 | Method for producing optically active fluorinated oxetane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8809557-B2 | Method for producing optically active fluorinated oxetane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| EP-2402328-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE FLUORINATED OXETANE | Tokyo Institute of Technology (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-20110306781-A1 | Method for Producing Optically Active Fluorinated Oxetane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-12-15 | — | — | US | disclosed |
| US-20110306781-A1 | Method for Producing Optically Active Fluorinated Oxetane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306781-A1 | Method for Producing Optically Active Fluorinated Oxetane | OXER1, FTO, CYP51A1 | ATM 4506/4885POLB 3279/4885OPRM1 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.