Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GUCY1A1 | Q02108 | 16/20 | 0.36 |
| ▸ | GUCY1B1 | Q02153 | 16/20 | 0.36 |
| ▸ | GUCY1B2 | O75343 | 3/20 | 0.36 |
| ▸ | GUCY1A2 | P33402 | 3/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437513 | 0.79 | GUCY1B2 (0.47) | L3MBTL1ADORA3KCNH2TSHRGUCY1A1 | |
| SCHEMBL3437473 | 0.77 | GUCY1B2 (0.49) | L3MBTL1ADORA3KCNH2TSHRGUCY1A1 | |
| SCHEMBL3437390 | 0.76 | GUCY1A1 (0.43) | L3MBTL1ADORA3KCNH2TSHRGUCY1A1 | |
| SCHEMBL3437479 | 0.76 | GUCY1B2 (0.44) | L3MBTL1ADORA3KCNH2TSHRGUCY1A1 | |
| SCHEMBL16081971 | 0.76 | GUCY1B2 (0.65) | GUCY1A1GUCY1B1GUCY1B2GUCY1A2OPRK1 | |
| SCHEMBL3437352 | 0.74 | GUCY1B2 (0.53) | L3MBTL1ADORA3KCNH2GUCY1A1GUCY1B1 | |
| SCHEMBL12298808 | 0.72 | PDE5A (0.52) | L3MBTL1ADORA3KCNH2TSHRGUCY1A1 | |
| SCHEMBL23186729 | 0.71 | ADORA3 (0.54) | L3MBTL1ADORA3KCNH2TSHRGUCY1A1 | |
| SCHEMBL23186730 | 0.71 | KCNH2 (0.52) | L3MBTL1ADORA3KCNH2TSHRGUCY1A1 | |
| SCHEMBL23186734 | 0.71 | GUCY1A1 (0.56) | ADORA3KCNH2GUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003405-A1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |