Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | FLT4 | P35916 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748143 | 0.84 | POLB (0.50) | SMN1; SMN2TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL3437085 | 0.82 | KDM4E (0.42) | ALDH1A1KDM4EKMT2AHSD17B10CYP1A2 | |
| SCHEMBL3437042 | 0.80 | KDM4E (0.48) | SMN1; SMN2TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL6129283 | 0.78 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL8754734 | 0.78 | GAA (0.38) | TSHRALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL1548854 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1ALDH1A1L3MBTL1 | |
| Ethane SCHEMBL7194508 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1L3MBTL1 | |
| SCHEMBL7556650 | 0.75 | TSHR (0.49) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL27549003 | 0.75 | KDM4E (0.38) | TSHRALDH1A1L3MBTL1KDM4EHSD17B10 | |
| SCHEMBL8754785 | 0.74 | POLB (0.39) | SMN1; SMN2TSHRALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649830-A | Substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-08-03 | — | — | CN | claimed |
| US-20050153958-A1 | SUBSTITUTED ARYL KETONES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-07-14 | — | — | US | claimed |
| US-7807703-B2 | Herbicides; pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-05 | — | — | US | disclosed |
| CN-1649830-A | Substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-08-03 | — | — | CN | disclosed |
| US-20050153958-A1 | SUBSTITUTED ARYL KETONES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-07-14 | — | — | US | disclosed |
| CN-1148385-A | 4-benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-23 | — | — | CN | disclosed |
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153958-A1 | SUBSTITUTED ARYL KETONES | CYP1A1, CBR3, DDT | SMN1; SMN2 3482/4885TSHR 269/4885CASP1 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.