Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747756 | 0.85 | CFTR (0.53) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL3437085 | 0.81 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1ACLYPTGDR2 | |
| SCHEMBL5833823 | 0.81 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDUSP2 | |
| SCHEMBL8755009 | 0.80 | GRM5 (0.39) | KDM4EALDH1A1PTGDR2MAPT | |
| SCHEMBL421582 | 0.79 | ALDH1A1 (0.59) | KDM4EHSD17B10ALDH1A1HPGDUSP2 | |
| SCHEMBL3437202 | 0.78 | SMN1; SMN2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDACLY | |
| SCHEMBL7636060 | 0.77 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDUSP2 | |
| SCHEMBL3437042 | 0.76 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1USP2CYP1A2 | |
| SCHEMBL9995051 | 0.75 | ALDH1A1 (0.54) | KDM4EHSD17B10ALDH1A1HPGDUSP2 | |
| SCHEMBL7557948 | 0.74 | ALDH1A1 (0.50) | KDM4EHSD17B10ALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649830-B | Substituted aryl ketones | BAYER CROPSCIENCE AG | 2014-05-14 | — | — | CN | claimed |
| CN-1649830-A | Substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-08-03 | — | — | CN | claimed |
| US-20050153958-A1 | SUBSTITUTED ARYL KETONES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-07-14 | — | — | US | claimed |
| CN-1649830-B | Substituted aryl ketones | BAYER CROPSCIENCE AG | 2014-05-14 | — | — | CN | disclosed |
| CN-1649830-A | Substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-08-03 | — | — | CN | disclosed |
| CN-1148385-A | 4-benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-23 | — | — | CN | disclosed |
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153958-A1 | SUBSTITUTED ARYL KETONES | CYP1A1, CBR3, DDT | KDM4E 402/4885HSD17B10 582/4885ALDH1A1 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.