SCHEMBL3437357

SCHEMBL3437357

CCCCC1CCC(CCc2ccc(OCC)c(F)c2F)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
HRH3 Q9Y5N1 1/20 0.34
KDM1A O60341 2/20 0.33
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPK1 P28482 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9405819 1.00 CYP1A2 (0.35) CYP1A2HRH3KDM1ACTSLCTSS
SCHEMBL3437343 0.96 CYP1A2 (0.33) CYP1A2HRH3KDM1ACTSLCTSS
SCHEMBL8455544 0.96 KDM1A (0.33) CYP1A2HRH3KDM1ACTSLCTSS
SCHEMBL8455541 0.96 KDM1A (0.33) CYP1A2HRH3KDM1ACTSLCTSS
SCHEMBL8448566 0.95 CNR2 (0.34) KDM1ACTSLCTSSCTSKGAA
SCHEMBL8448569 0.95 CNR2 (0.34) KDM1ACTSLCTSSCTSKGAA
SCHEMBL3437342 0.92 CNR2 (0.31) KDM1ACTSLCTSSCTSKGAA
SCHEMBL22277554 0.92 CNR2 (0.31) KDM1ACTSLCTSSCTSKGAA
SCHEMBL9405829 0.92 KDM1A (0.35) HRH3KDM1ACTSLCTSSCTSK
SCHEMBL3437363 0.92 KDM1A (0.35) HRH3KDM1ACTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10519377-B1 Liquid crystal composition of negative monomer containing cyclopentyl cyclohexenyl and liquid crystal display element or liquid crystal display thereof Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd (CN) 2019-12-31 US disclosed
US-20120097895-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2012-04-26 US disclosed
US-20120097895-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2012-04-26 US disclosed
US-5279764-A Dihalogenobenzene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-01-18 US disclosed