SCHEMBL8448569

SCHEMBL8448569

CCCCCCCC1CCC(CCc2ccc(OCC)c(F)c2F)CC1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 11/20 0.34
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CNR1 P21554 7/20 0.33
KDM1A O60341 2/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C8 P10632 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
S1PR3 Q99500 1/20 0.31
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8448566 1.00 CNR2 (0.34) CNR2GAAMAPTCNR1KDM1A
SCHEMBL8455541 0.99 KDM1A (0.33) CNR2GAAMAPTCNR1KDM1A
SCHEMBL8455544 0.99 KDM1A (0.33) CNR2GAAMAPTCNR1KDM1A
SCHEMBL22277554 0.95 CNR2 (0.31) CNR2GAAMAPTCNR1KDM1A
SCHEMBL3437342 0.95 CNR2 (0.31) CNR2GAAMAPTCNR1KDM1A
SCHEMBL3437357 0.95 CYP1A2 (0.35) GAAMAPTKDM1ACYP2D6CYP2C9
SCHEMBL9405819 0.95 CYP1A2 (0.35) GAAMAPTKDM1ACYP2D6CYP2C9
SCHEMBL3437343 0.91 CYP1A2 (0.33) GAAMAPTKDM1ACYP2D6CYP2C9
SCHEMBL9405938 0.91 RIPK1 (0.38) CNR2GAAMAPTCNR1CTSL
SCHEMBL9405934 0.91 RIPK1 (0.38) CNR2GAAMAPTCNR1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5980778-A STABILITY, COMPATIBILITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0768361-A1 Liquid crystal composition and liquid crystal display element comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-04-16 EP disclosed