SCHEMBL3437396

SCHEMBL3437396

Cc1ccc(N=Nc2ccc(N=Nc3ccc(N=Nc4ccc(N=Nc5ccc(N=Nc6ccc(N(C)C)cc6)cc5C)cc4C)cc3C)cc2C)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.58
RAB9A P51151 10/20 0.58
KMT2A Q03164 8/20 0.58
MEN1 O00255 7/20 0.58
TDP1 Q9NUW8 5/20 0.58
CASP3 P42574 2/20 0.58
SENP8 Q96LD8 2/20 0.58
SENP7 Q9BQF6 2/20 0.58
SENP6 Q9GZR1 2/20 0.58
NSD2 O96028 1/20 0.58
MAPK1 P28482 6/20 0.53
MAPT P10636 4/20 0.53
L3MBTL1 Q9Y468 4/20 0.53
ATM Q13315 2/20 0.53
ALDH1A1 P00352 4/20 0.50
TSHR P16473 3/20 0.50
HSD17B10 Q99714 1/20 0.50
ALPL P05186 1/20 0.49
ALPI P09923 1/20 0.49
ALPG P10696 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14866700 1.00 NPC1 (0.58) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL10216010 1.00 NPC1 (0.58) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL11048726 0.95 NPC1 (0.59) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL11048735 0.95 NPC1 (0.59) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL11048731 0.95 NPC1 (0.59) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL13259650 0.90 NPC1 (0.54) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL11036686 0.89 MAPK1 (0.68) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL327807 0.87 NPC1 (0.58) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL12069744 0.87 NPC1 (0.58) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL15677255 0.87 NPC1 (0.54) NPC1RAB9AKMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160280999-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2016-09-29 US disclosed
US-9382481-B2 Polarizing film, display device and production process thereof FUJIFILM CORPORATION (JP) 2016-07-05 US disclosed
US-9011988-B2 Liquid-crystal compound, liquid-crystal composition, light absorption anisotropic film, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-8927070-B2 Dichroic dye composition, light absorption anisotropic film, and polarizing element FUJIFILM CORPORATION (JP) 2015-01-06 US disclosed
US-8865275-B2 Light absorption anisotropic film, polarizing film, process for producing the polarizing film and display device using the polarizing film FUJIFILM CORPORATION (JP) 2014-10-21 US disclosed
US-8728976-B2 Printing paper for printing stereoscopic image, stereoscopic image printed matter, and method for providing stereoscopic image FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8541935-B2 Color filter and light-emitting display element UDC IRELAND LIMITED (IE) 2013-09-24 US disclosed
US-20130187090-A1 LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION, LIGHT ABSORPTION ANISOTROPIC FILM, AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-07-25 US disclosed
US-20130169896-A1 STEREO IMAGE PRINT AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2013-07-04 US disclosed
US-20130120676-A1 STEREO IMAGE PRINT AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2013-05-16 US disclosed
US-20130107195-A1 LIGHT ABSORPTION ANISOTROPIC FILM, POLARIZING FILM, PROCESS FOR PRODUCING THE POLARIZING FILM AND DISPLAY DEVICE USING THE POLARIZING FILM FUJIFILM CORPORATION (JP) 2013-05-02 US disclosed
US-20130083276-A1 PRINTING SHEET FOR PRINTING STEREO PICTURE, STEREO PICTURE PRINT, METHOD OF MANUFACTURING STEREO PICTURE PRINT, AND METHOD OF PROVIDING STEREO PICTURE FUJIFILM CORPORATION (JP) 2013-04-04 US disclosed
US-20130070899-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2013-03-21 US disclosed
US-20120099054-A1 COLOR FILTER AND LIGHT-EMITTING DISPLAY ELEMENT UDC IRELAND LIMITED (IE) 2012-04-26 US disclosed
US-20110177315-A1 DICHROIC DYE COMPOSITION, LIGHT ABSORPTION ANISOTROPIC FILM, AND POLARIZING ELEMENT FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed
US-20090274853-A1 DICHROIC DYE COMPOSITION FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274853-A1 DICHROIC DYE COMPOSITION C1S, CDY1; CDY1B, CRY1 NPC1 1911/4885RAB9A 2474/4885KMT2A 2439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.