SCHEMBL3437402

SCHEMBL3437402

CCCCc1ccc(N=Nc2ccc(N=Nc3cc(C)c(N=Nc4ccc(N(CC)CC)cc4)cc3C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.42
CYP2D6 P10635 4/20 0.42
CYP2C9 P11712 4/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
CYP4Z1 Q86W10 1/20 0.42
CYP4F11 Q9HBI6 1/20 0.42
CYP4F12 Q9HCS2 1/20 0.42
MAPT P10636 5/20 0.41
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
KMT2A Q03164 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
SKP2 Q13309 1/20 0.38
PSMD14 O00487 1/20 0.38
MITF O75030 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10216442 0.92 CYP3A4 (0.43) CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19
SCHEMBL16125397 0.92 CYP3A4 (0.43) CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19
SCHEMBL10215989 0.92 CYP3A4 (0.43) CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19
SCHEMBL15082780 0.92 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19
SCHEMBL3437423 0.91 CYP3A4 (0.44) CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19
SCHEMBL25485920 0.89 TDP1 (0.49) CYP3A4CYP2D6CYP2C9MAPTRAB9A
SCHEMBL26392552 0.89 TDP1 (0.49) CYP3A4CYP2D6CYP2C9MAPTRAB9A
SCHEMBL19930176 0.89 TDP1 (0.49) CYP3A4CYP2D6CYP2C9MAPTRAB9A
SCHEMBL3437419 0.89 TDP1 (0.49) CYP3A4CYP2D6CYP2C9MAPTRAB9A
SCHEMBL7534641 0.86 CYP3A4 (0.42) CYP3A4CYP2D6CYP2C9CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160280999-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2016-09-29 US disclosed
US-20160280999-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2016-09-29 US disclosed
US-9382481-B2 Polarizing film, display device and production process thereof FUJIFILM CORPORATION (JP) 2016-07-05 US disclosed
US-9382481-B2 Polarizing film, display device and production process thereof FUJIFILM CORPORATION (JP) 2016-07-05 US disclosed
US-9011988-B2 Liquid-crystal compound, liquid-crystal composition, light absorption anisotropic film, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-9011988-B2 Liquid-crystal compound, liquid-crystal composition, light absorption anisotropic film, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-8927070-B2 Dichroic dye composition, light absorption anisotropic film, and polarizing element FUJIFILM CORPORATION (JP) 2015-01-06 US disclosed
US-8927070-B2 Dichroic dye composition, light absorption anisotropic film, and polarizing element FUJIFILM CORPORATION (JP) 2015-01-06 US disclosed
US-8865275-B2 Light absorption anisotropic film, polarizing film, process for producing the polarizing film and display device using the polarizing film FUJIFILM CORPORATION (JP) 2014-10-21 US disclosed
US-8865275-B2 Light absorption anisotropic film, polarizing film, process for producing the polarizing film and display device using the polarizing film FUJIFILM CORPORATION (JP) 2014-10-21 US disclosed
US-20110177315-A1 DICHROIC DYE COMPOSITION, LIGHT ABSORPTION ANISOTROPIC FILM, AND POLARIZING ELEMENT FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed
US-20110177315-A1 DICHROIC DYE COMPOSITION, LIGHT ABSORPTION ANISOTROPIC FILM, AND POLARIZING ELEMENT FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed
US-20110051052-A1 POLARIZING FILM, LAMINATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110051052-A1 POLARIZING FILM, LAMINATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20100182543-A1 LIQUID CRYSTALLINE COMPOSITION AND LIGHT ABSORPTION ANISOTROPIC FILM, A POLARIZING ELEMENT AND A LIQUID CRYSTAL DISPLAY DEVICE, EACH EMPLOYING THE SAME FUJIFILM CORPORATION (JP) 2010-07-22 US disclosed
US-20100182543-A1 LIQUID CRYSTALLINE COMPOSITION AND LIGHT ABSORPTION ANISOTROPIC FILM, A POLARIZING ELEMENT AND A LIQUID CRYSTAL DISPLAY DEVICE, EACH EMPLOYING THE SAME FUJIFILM CORPORATION (JP) 2010-07-22 US disclosed
US-20100134726-A1 POLARIZING ELEMENT AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-06-03 US disclosed
US-20100134726-A1 POLARIZING ELEMENT AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-06-03 US disclosed
US-20090274853-A1 DICHROIC DYE COMPOSITION FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090274853-A1 DICHROIC DYE COMPOSITION FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274853-A1 DICHROIC DYE COMPOSITION C1S, CDY1; CDY1B, CRY1 CYP3A4 462/4885CYP2D6 714/4885CYP2C9 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.