SCHEMBL3437517

SCHEMBL3437517

O=C(O)c1ccc(/N=N/c2ccc(-c3ccc(/N=N/c4cccc(O)c4)cc3S(=O)(=O)O)cc2)cc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
APP P05067 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
GLO1 Q04760 4/20 0.43
PHLPP2 Q6ZVD8 5/20 0.41
HSD17B10 Q99714 3/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
CYP2C19 P33261 1/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 1/20 0.40
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
MAPT P10636 1/20 0.40
CA12 O43570 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15267910 0.84 HSD17B10 (0.50) MEN1KMT2AAPPTHRBRECQL
SCHEMBL12374421 0.82 MEN1 (0.67) MEN1KMT2AAPPTHRBRECQL
SCHEMBL12374379 0.82 ALDH1A1 (0.56) MEN1KMT2AAPPTHRBRECQL
SCHEMBL3708516 0.82 ALDH1A1 (0.56) MEN1KMT2AAPPTHRBRECQL
SCHEMBL19929460 0.81 MEN1 (0.62) MEN1KMT2AAPPTHRBRECQL
SCHEMBL16575029 0.81 MEN1 (0.62) MEN1KMT2AAPPTHRBRECQL
SCHEMBL17131772 0.81 NPC1 (0.46) MEN1KMT2AAPPTHRBRECQL
SCHEMBL16016694 0.75 MEN1 (0.60) MEN1KMT2AAPPTHRBRECQL
SCHEMBL28564385 0.74 MAPT (0.50) MEN1KMT2AAPPTHRBRECQL
SCHEMBL14391860 0.74 MEN1 (0.68) MEN1KMT2AAPPTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541935-B2 Color filter and light-emitting display element UDC IRELAND LIMITED (IE) 2013-09-24 US disclosed
US-20120099054-A1 COLOR FILTER AND LIGHT-EMITTING DISPLAY ELEMENT UDC IRELAND LIMITED (IE) 2012-04-26 US disclosed