Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21964515 | 0.84 | L3MBTL1 (0.46) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL31134749 | 0.83 | L3MBTL1 (0.45) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL30548022 | 0.78 | L3MBTL1 (0.45) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL23748055 | 0.78 | L3MBTL1 (0.45) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL1196432 | 0.77 | L3MBTL1 (0.62) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL15902467 | 0.76 | L3MBTL1 (0.44) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL29443977 | 0.76 | L3MBTL1 (0.44) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL10819499 | 0.75 | L3MBTL1 (0.57) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL29651127 | 0.75 | L3MBTL1 (0.57) | L3MBTL1BRD4CREBBPBCHEHTR6 | |
| SCHEMBL18788881 | 0.74 | L3MBTL1 (0.44) | L3MBTL1BRD4CREBBPBCHEHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001308-A9 | METHOD FOR SYNTHESIZING ERGOLINE ALKALOIDS FROM INDOLIC BICYCLIC COMPOUNDS BY DOUBLE CYCLIZATION, RESULTING MATERIALS, AND INTERMEDIATE MATERIALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012001308-A1 | METHOD FOR SYNTHESIZING ERGOLINE ALKALOIDS FROM INDOLIC BICYCLIC COMPOUNDS BY DOUBLE CYCLIZATION, RESULTING MATERIALS, AND INTERMEDIATE MATERIALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-01-05 | — | — | WO | disclosed |