Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407014 | 0.81 | CA1 (0.39) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL4559895 | 0.81 | CA1 (0.39) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL1568359 | 0.76 | — | — | |
| SCHEMBL6912662 | 0.76 | — | — | |
| SCHEMBL181970 | 0.76 | — | — | |
| SCHEMBL6529834 | 0.75 | — | — | |
| SCHEMBL7871650 | 0.75 | CA1 (0.48) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL5194718 | 0.75 | CA1 (0.48) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL8578128 | 0.75 | MAOA (0.34) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL9874961 | 0.74 | KMT2A (0.52) | CA1CA2CA4KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040119-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP ASSETS BV (NL) | 2021-02-11 | — | — | US | claimed |
| EP-3293187-A1 | A PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP Assets B.V. (NL) | 2018-03-14 | — | — | EP | claimed |
| US-20180065990-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP ASSETS B.V. (NL) | 2018-03-08 | — | — | US | claimed |
| EP-1219625-B1 | Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- perhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds | COUNCIL SCIENT IND RES (IN) | 2006-05-17 | — | — | EP | claimed |
| US-6486328-B1 | Substituted 2-[-6-benzyl-5-oxo-3-phenyl-(3s,7s, 7aR)-perhydroimidazol[1,5-c][1,3]thiazol-7yl] compounds | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-11-26 | — | — | US | claimed |
| EP-1219625-A1 | Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- pherhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds | Council of Scientific and Industrial Research (IN) | 2002-07-03 | — | — | EP | claimed |
| US-20210040119-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP ASSETS BV (NL) | 2021-02-11 | — | — | US | disclosed |
| EP-3293187-A1 | A PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP Assets B.V. (NL) | 2018-03-14 | — | — | EP | disclosed |
| US-20180065990-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP ASSETS B.V. (NL) | 2018-03-08 | — | — | US | disclosed |
| WO-2016146689-A1 | ORGANOZINC REAGENTS AND PROCESSES FOR PREPARING AND USING THE SAME | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2016-09-22 | — | — | WO | disclosed |
| WO-2016146689-A1 | ORGANOZINC REAGENTS AND PROCESSES FOR PREPARING AND USING THE SAME | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2016-09-22 | — | — | WO | disclosed |
| EP-3070083-A1 | Organozinc reagents and processes for preparing and using the same | Ludwig-Maximilians-Universität München (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-3070083-A1 | Organozinc reagents and processes for preparing and using the same | Ludwig-Maximilians-Universität München (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-7807856-B2 | Process for production of 2-Benzylphenol compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20080194882-A1 | Process For Production of 2-Benzylphenol Compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1810957-A1 | METHOD FOR PRODUCING 2-BENZYLPHENOL COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2007-07-25 | — | — | EP | disclosed |
| EP-1219625-B1 | Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- perhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds | COUNCIL SCIENT IND RES (IN) | 2006-05-17 | — | — | EP | disclosed |
| US-6486328-B1 | Substituted 2-[-6-benzyl-5-oxo-3-phenyl-(3s,7s, 7aR)-perhydroimidazol[1,5-c][1,3]thiazol-7yl] compounds | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-11-26 | — | — | US | disclosed |
| EP-1219625-A1 | Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- pherhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds | Council of Scientific and Industrial Research (IN) | 2002-07-03 | — | — | EP | disclosed |
| WO-1993006071-A1 | PREPARATION OF MANGANOUS ENOLATES AND APPLICATIONS THEREOF | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1993-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194882-A1 | Process For Production of 2-Benzylphenol Compound | CYP1B1, CYP4B1, CYP1A1 | CA1 4585/4885CA2 3274/4885CA4 2549/4885 |
| US-20210040119-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | ABL1, KRAS, FLI1 | CA1 360/4885CA2 776/4885CA4 79/4885 |
| US-20180065990-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | ABL1, KRAS, FLI1 | CA1 357/4885CA2 778/4885CA4 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.