SCHEMBL3438583

SCHEMBL3438583

CCOC(=O)c1ccc(OC(=O)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.57
ACR P10323 1/20 0.57
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
CA12 O43570 2/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA9 Q16790 2/20 0.51
ESR1 P03372 1/20 0.51
CA7 P43166 1/20 0.51
ESR2 Q92731 1/20 0.51
CA14 Q9ULX7 1/20 0.51
RAB9A P51151 4/20 0.51
NPC1 O15118 3/20 0.51
TP53 P04637 1/20 0.51
POLB P06746 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
LMNA P02545 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65692 0.91 CA12 (0.61) KMT2AMEN1CA12CA1CA2
SCHEMBL15315056 0.88 MAPT (0.58) PRSS1ACRKMT2AMEN1ESR1
SCHEMBL10344282 0.87 PRSS1 (0.69) PRSS1ACRKMT2AMEN1CA12
SCHEMBL3626698 0.86 RARB (0.47) KMT2AMEN1CA1CA2POLB
SCHEMBL9762354 0.84 MAPT (0.54) PRSS1ACRKMT2AMEN1RAB9A
SCHEMBL1546363 0.84 KMT2A (0.59) KMT2AMEN1RAB9ANPC1MAPT
SCHEMBL18254165 0.84 PRSS1 (0.49) PRSS1ACRKMT2AMEN1RAB9A
SCHEMBL3438584 0.82 KMT2A (0.44) PRSS1ACRKMT2AMEN1POLB
SCHEMBL8205439 0.82 PRSS1 (0.64) PRSS1ACRKMT2AMEN1CA12
SCHEMBL18821734 0.82 RAB9A (0.64) PRSS1ACRKMT2AMEN1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9182632-B2 Liquid crystal display device and method for manufacturing liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2015-11-10 US disclosed
US-9182632-B2 Liquid crystal display device and method for manufacturing liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2015-11-10 US disclosed
US-20130271712-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2013-10-17 US disclosed
US-20130271712-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2013-10-17 US disclosed
US-20120092603-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREFOR SHARP KABUSHIKI KAISHA (JP) 2012-04-19 US disclosed
US-20120092603-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREFOR SHARP KABUSHIKI KAISHA (JP) 2012-04-19 US disclosed