Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850976 | 0.81 | MEN1 (0.37) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL11237533 | 0.79 | TSHR (0.37) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL28899886 | 0.77 | TSHR (0.42) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL30620386 | 0.77 | TSHR (0.42) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL2430576 | 0.77 | TSHR (0.42) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL23579190 | 0.77 | TSHR (0.42) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL30094966 | 0.77 | TSHR (0.42) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL3707759 | 0.76 | MEN1 (0.39) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL3707762 | 0.74 | MEN1 (0.36) | MEN1KMT2AMAPTATML3MBTL1 | |
| Bicarbonate SCHEMBL28473664 | 0.74 | CES2 (0.44) | MEN1KMT2ACES2GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731307-B1 | SEPARATOR WITHOUT SEPARATOR SUBSTRATE | LG ENERGY SOLUTION LTD (KR) | 2025-12-24 | — | — | EP | claimed |
| US-12308471-B2 | Separator having no separator substrate and electrochemical device including the same | LG ENERGY SOLUTION, LTD. (KR) | 2025-05-20 | — | — | US | claimed |
| US-20240291106-A1 | SEPARATOR HAVING NO SEPARATOR SUBSTRATE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | LG ENERGY SOLUTION, LTD. (KR) | 2024-08-29 | — | — | US | claimed |
| US-12054595-B2 | Method for improving physical properties of separator by post-treatment crosslinking and separator prepared thereby | LG ENERGY SOLUTION, LTD. (KR) | 2024-08-06 | — | — | US | claimed |
| US-11929520-B2 | Porous separator without polyolefin substrate including inorganic particles and polymer binder | LG ENERGY SOLUTION, LTD. (KR) | 2024-03-12 | — | — | US | claimed |
| EP-3624224-B1 | SEPARATOR WITHOUT SEPARATOR SUBSTRATE AND ELECTROCHEMICAL DEVICE COMPRISING SAME | LG ENERGY SOLUTION LTD (KR) | 2023-10-04 | — | — | EP | claimed |
| CN-115850895-A | Continuous fiber reinforced PMMA composite material and preparation method and application thereof | 郑州中科新兴产业技术研究院 | 2023-03-28 | — | — | CN | claimed |
| CN-115819653-A | Continuous fiber reinforced PMMA (polymethyl methacrylate) composite material as well as preparation method and application thereof | 郑州中科新兴产业技术研究院 | 2023-03-21 | — | — | CN | claimed |
| CN-110651383-B | Separator without separator substrate and electrochemical device comprising same | 株式会社LG新能源 | 2022-11-29 | — | — | CN | claimed |
| CN-111527624-B | Separator without separator substrate | 株式会社LG新能源 | 2022-11-18 | — | — | CN | claimed |
| US-20210005859-A1 | SEPARATOR HAVING NO SEPARATOR SUBSTRATE | LG CHEM, LTD. (KR) | 2021-01-07 | — | — | US | claimed |
| US-20200358065-A1 | SEPARATOR HAVING NO SEPARATOR SUBSTRATE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | LG CHEM, LTD. (KR) | 2020-11-12 | — | — | US | claimed |
| EP-3731307-A1 | SEPARATOR WITHOUT SEPARATOR SUBSTRATE | LG CHEM, LTD. (KR) | 2020-10-28 | — | — | EP | claimed |
| US-20200287187-A1 | METHOD FOR IMPROVING PHYSICAL PROPERTIES OF SEPARATOR BY POST-TREATMENT CROSSLINKING AND SEPARATOR PREPARED THEREBY | LG CHEM, LTD. (KR) | 2020-09-10 | — | — | US | claimed |
| CN-111527624-A | Separator without separator substrate | 株式会社LG化学 | 2020-08-11 | — | — | CN | claimed |
| CN-107254015-B | Thermosetting resin-based fiber composite material and preparation method thereof | 东华大学 | 2020-08-04 | — | — | CN | claimed |
| EP-3663337-A1 | METHOD FOR IMPROVING PROPERTIES OF SEPARATOR THROUGH POST-TREATMENT CROSSLINKING AND SEPARATOR THEREBY | LG CHEM, LTD. (KR) | 2020-06-10 | — | — | EP | claimed |
| CN-110914346-A | Method for improving physical properties of separator by post-treatment crosslinking and separator prepared thereby | 株式会社LG化学 | 2020-03-24 | — | — | CN | claimed |
| EP-3624224-A2 | SEPARATOR WITHOUT SEPARATOR SUBSTRATE AND ELECTROCHEMICAL DEVICE COMPRISING SAME | LG Chem, Ltd. (KR) | 2020-03-18 | — | — | EP | claimed |
| CN-110651383-A | Separator without separator substrate and electrochemical device comprising same | 株式会社LG化学 | 2020-01-03 | — | — | CN | claimed |