Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10301413 | 0.86 | KMT2A (0.44) | PRSS1PRSS2PRSS3ELANEKMT2A | |
| SCHEMBL14180053 | 0.80 | PRSS1 (0.47) | PRSS1PRSS2PRSS3ELANEKMT2A | |
| SCHEMBL5161147 | 0.80 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL21879662 | 0.80 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL3680357 | 0.80 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL25297232 | 0.80 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL43568 | 0.80 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL20564639 | 0.80 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL1531270 | 0.80 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL3165609 | 0.80 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160250374-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ORTHOCON, INC. | 2016-09-01 | — | — | US | disclosed |
| US-9314547-B2 | Absorbable multi-putty bone cements and hemostatic compositions and methods of use | ABYRX INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-9174924-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-9174924-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150259275-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2015-09-17 | — | — | US | disclosed |
| US-20150259275-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL LLC (US) | 2015-09-17 | — | — | US | disclosed |
| US-9045396-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-9045396-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-20120197037-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2012-08-02 | — | — | US | disclosed |
| US-8232422-B2 | Functionalized biodegradable triclosan monomers and oligomers for controlled release | BEZWADA BIOMEDICAL, LLC (US) | 2012-07-31 | — | — | US | disclosed |
| US-20120095114-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | BEZWADA BIOMEDICAL, LLC (US) | 2012-04-19 | — | — | US | disclosed |
| US-8053591-B2 | Functionalized biodegradable triclosan monomers and oligomers for controlled release | BEZWADA BIOMEDICAL, LLC (US) | 2011-11-08 | — | — | US | disclosed |
| US-8048980-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2011-11-01 | — | — | US | disclosed |
| US-8048980-B2 | Hydrolysable linkers and cross-linkers for absorbable polymers | BEZWADA BIOMEDICAL, LLC (US) | 2011-11-01 | — | — | US | disclosed |
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2009-11-19 | — | — | US | disclosed |
| US-20090105352-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | BEZWADA BIOMEDICAL, LLC (US) | 2009-04-23 | — | — | US | disclosed |
| US-20090082540-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2009-03-26 | — | — | US | disclosed |
| US-20090082540-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | BEZWADA BIOMEDICAL, LLC (US) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259275-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | PRSS1 1347/4885PRSS2 579/4885PRSS3 592/4885 |
| US-20120197037-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | PRSS1 1347/4885PRSS2 579/4885PRSS3 592/4885 |
| US-20090105352-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | LTN1, PARN, TLR3 | PRSS1 763/4885PRSS2 1356/4885PRSS3 1521/4885 |
| US-20090082540-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | PRSS1 1347/4885PRSS2 579/4885PRSS3 592/4885 |
| US-20120095114-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | LTN1, PARN, TLR3 | PRSS1 763/4885PRSS2 1356/4885PRSS3 1521/4885 |
| US-20160023998-A1 | HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS | SI, KDM8, APEH | PRSS1 1347/4885PRSS2 579/4885PRSS3 592/4885 |
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | PAICS, UROD, PUF60 | PRSS1 1977/4885PRSS2 1703/4885PRSS3 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.