Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117203 | 0.89 | SMN1; SMN2 (0.50) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL6910695 | 0.86 | TSHR (0.72) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL11255192 | 0.86 | TSHR (0.72) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL2117939 | 0.83 | SMN1; SMN2 (0.54) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL16299847 | 0.78 | TSHR (0.53) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL3438960 | 0.78 | SMN1; SMN2 (0.48) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL29996006 | 0.76 | SMN1; SMN2 (0.65) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL29106733 | 0.76 | SMN1; SMN2 (0.65) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL10445559 | 0.76 | SMN1; SMN2 (0.65) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL11393637 | 0.74 | TSHR (0.51) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399696-B2 | Functionalized biodegradable triclosan monomers and oligomers for controlled release | BEZWADA BIOMEDICAL, LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399696-B2 | Functionalized biodegradable triclosan monomers and oligomers for controlled release | BEZWADA BIOMEDICAL, LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120289614-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | BEZWADA BIOMEDICAL, LLC (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120289614-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | BEZWADA BIOMEDICAL, LLC (US) | 2012-11-15 | — | — | US | disclosed |
| US-8232422-B2 | Functionalized biodegradable triclosan monomers and oligomers for controlled release | BEZWADA BIOMEDICAL, LLC (US) | 2012-07-31 | — | — | US | disclosed |
| US-8232422-B2 | Functionalized biodegradable triclosan monomers and oligomers for controlled release | BEZWADA BIOMEDICAL, LLC (US) | 2012-07-31 | — | — | US | disclosed |
| US-20120095114-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | BEZWADA BIOMEDICAL, LLC (US) | 2012-04-19 | — | — | US | disclosed |
| US-20120095114-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | BEZWADA BIOMEDICAL, LLC (US) | 2012-04-19 | — | — | US | disclosed |
| US-8053591-B2 | Functionalized biodegradable triclosan monomers and oligomers for controlled release | BEZWADA BIOMEDICAL, LLC (US) | 2011-11-08 | — | — | US | disclosed |
| US-8053591-B2 | Functionalized biodegradable triclosan monomers and oligomers for controlled release | BEZWADA BIOMEDICAL, LLC (US) | 2011-11-08 | — | — | US | disclosed |
| US-20090105352-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | BEZWADA BIOMEDICAL, LLC (US) | 2009-04-23 | — | — | US | disclosed |
| US-20090105352-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | BEZWADA BIOMEDICAL, LLC (US) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105352-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | LTN1, PARN, TLR3 | TSHR 2565/4885HTR2A 767/4885HTR2C 1493/4885 |
| US-20120095114-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | LTN1, PARN, TLR3 | TSHR 2565/4885HTR2A 767/4885HTR2C 1493/4885 |
| US-20120289614-A1 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE | LTN1, PARN, TLR3 | TSHR 2565/4885HTR2A 767/4885HTR2C 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.