SCHEMBL11255192

SCHEMBL11255192

COC(=O)C(C)Oc1ccc(Cl)cc1C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.72
HTR2A P28223 1/20 0.72
HTR2C P28335 1/20 0.72
HTR2B P41595 1/20 0.72
SMN1; SMN2 Q16637 7/20 0.59
LMNA P02545 6/20 0.59
MAPT P10636 4/20 0.59
HTT P42858 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
ALOX12 P18054 1/20 0.59
TRPM4 Q8TD43 1/20 0.59
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
KMT2A Q03164 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ATM Q13315 1/20 0.52
MAPK1 P28482 1/20 0.50
GAA P10253 1/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6910695 1.00 TSHR (0.72) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
SCHEMBL11874266 0.86 TSHR (0.70) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
SCHEMBL21056076 0.86 TSHR (0.70) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
SCHEMBL30754255 0.86 TSHR (0.70) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
SCHEMBL29106733 0.86 SMN1; SMN2 (0.65) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
SCHEMBL29996006 0.86 SMN1; SMN2 (0.65) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
SCHEMBL10445559 0.86 SMN1; SMN2 (0.65) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
SCHEMBL3438987 0.86 TSHR (0.54) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
SCHEMBL11393637 0.84 TSHR (0.51) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop-P SCHEMBL572351 0.84 TSHR (1.00) TSHRHTR2AHTR2CHTR2BSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337017-A1 HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS Bayer Aktiengesellschaft (DE) 2024-03-20 EP claimed
WO-2022152728-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2022-07-21 WO claimed
EP-4680598-A1 4-DIFLUOROMETHYL BENZAMIDES WITH HERBICIDAL ACTION Bayer Aktiengesellschaft (DE) 2026-01-21 EP disclosed
WO-2025224076-A1 SUBSTITUTED ARYLPYRAZINES AND SALTS THEREOF, AND USE THEREOF AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-10-30 WO disclosed
US-20250270581-A1 METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE MONSANTO TECHNOLOGY LLC (US) 2025-08-28 US disclosed
EP-4605379-A1 BROMINE- OR IODINE-PARA-SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND SALTS THEREOF, PROTECTION AGENTS COMPRISING THEM, FOR USEFUL PLANTS OR CROP PLANTS, METHODS FOR PRODUCING THEM AND USE THEREOF AS SAFENERS Bayer Aktiengesellschaft (DE) 2025-08-27 EP disclosed
EP-4605378-A2 BROMINE- OR IODINE-PARA-SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND THEIR SALTS, AGENTS FOR PROTECTING USEFUL PLANTS OR CROP PLANTS COMPRISING THEM, METHODS FOR PRODUCING THEM AND THEIR USE AS SAFENERS Bayer Aktiengesellschaft (DE) 2025-08-27 EP disclosed
EP-4602036-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2025-08-20 EP disclosed
US-20250241298-A1 Liquid Sulfonylurea-Containing Herbicidal Compositions BATTELLE UK LIMITED (GB) 2025-07-31 US disclosed
US-12364261-B2 Liquid sulfonylurea- and Li-salt containing herbicidal compositions BATTELLE UK LIMITED (GB) 2025-07-22 US disclosed
US-20250228243-A1 METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE MONSANTO TECHNOLOGY LLC (US) 2025-07-17 US disclosed
CN-114340393-A Herbicidal composition 拜耳公司 2022-04-12 CN disclosed
CN-114258929-A Baked bread and preparation method thereof 浙江华康药业股份有限公司 2022-04-01 CN disclosed
US-20220053762-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2022-02-24 US disclosed
EP-3890489-A1 HERBICIDE COMPOSITIONS Bayer Aktiengesellschaft (DE) 2021-10-13 EP disclosed
EP-3890488-A1 HERBICIDAL COMPOSITIONS Bayer Aktiengesellschaft (DE) 2021-10-13 EP disclosed
WO-2021001273-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2021-01-07 WO disclosed
WO-2020114934-A1 HERBICIDE COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2020-06-11 WO disclosed
WO-2020114932-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2020-06-11 WO disclosed
US-4314086-A FROM ALIPHATIC HALIDE WITH PHENOLATE OR NAPHTHOLATE IN PRESENCE OFTERTIARY AMINE SEQUESTERING AGENT RHONE-POULENC INDUSTRIES (FR) 1982-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12364261-B2 Liquid sulfonylurea- and Li-salt containing herbicidal compositions LCT, CLIC1, CLIC4 TSHR 841/4885HTR2A 3059/4885HTR2C 2009/4885
US-20220053762-A1 HERBICIDAL COMPOSITIONS DDT, GUSB, HDHD5 TSHR 2963/4885HTR2A 2906/4885HTR2C 2507/4885
US-20250270581-A1 METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE PPOX, PTPRG, PAOX TSHR 1317/4885HTR2A 1902/4885HTR2C 1293/4885
US-20250228243-A1 METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE UNG, PNPO, PPOX TSHR 2788/4885HTR2A 2174/4885HTR2C 1486/4885
US-20250241298-A1 Liquid Sulfonylurea-Containing Herbicidal Compositions CA2, CA3, DPP4 TSHR 1984/4885HTR2A 3578/4885HTR2C 2812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.