Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 13/20 | 0.53 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.48 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BIRC7 | Q96CA5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119703 | 0.92 | XIAP (0.53) | XIAPBIRC3BIRC2BIRC7 | |
| SCHEMBL10081737 | 0.90 | XIAP (0.54) | XIAPBIRC3BIRC2 | |
| SCHEMBL895868 | 0.90 | XIAP (0.54) | XIAPBIRC3BIRC2 | |
| SCHEMBL10066065 | 0.90 | XIAP (0.57) | XIAPBIRC3BIRC2OPRM1BIRC7 | |
| SCHEMBL15567009 | 0.90 | XIAP (0.55) | XIAPBIRC3BIRC2 | |
| SCHEMBL15567008 | 0.90 | XIAP (0.55) | XIAPBIRC3BIRC2 | |
| SCHEMBL895869 | 0.89 | XIAP (0.52) | XIAPBIRC3BIRC2LNPEP | |
| SCHEMBL3439205 | 0.89 | XIAP (0.45) | XIAPBIRC3BIRC2MEN1HTT | |
| SCHEMBL10081371 | 0.88 | XIAP (0.65) | XIAPBIRC3BIRC2BIRC7 | |
| SCHEMBL3439008 | 0.88 | XIAP (0.52) | XIAPBIRC3BIRC2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281385-A1 | SMALL MOLECULE APOPTOSIS PROMOTERS | JOYANT PHARMACEUTICALS, INC. | 2013-10-24 | — | — | US | disclosed |
| US-8222291-B2 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-7807699-B2 | Dimeric pyrrolidine amide-containing small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| EP-1996184-A2 | SMALL MOLECULE APOPTOSIS PROMOTERS | Joyant Pharmaceuticals, Inc. (US) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007136921-A2 | SMALL MOLECULE APOPTOSIS PROMOTERS | JOYANT PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281385-A1 | SMALL MOLECULE APOPTOSIS PROMOTERS | BID, BAD, BAX | XIAP 31/4885BIRC3 7/4885BIRC2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.